Sigma-Aldrich α-Zearalenol. ≥98% (HPLC), ERα agonist, powder. 5 mg

Name: Sigma-Aldrich α-Zearalenol. ≥98% (HPLC), ERα agonist, powder. 5 mg
SKU: SIAL-Z0166-5MG
Price: 490.68 USD

List Price $490.68 Your Price $490.68

Sigma-Aldrich α-Zearalenol. ≥98% (HPLC), ERα agonist, powder. 5 mg - SIAL (Additional S&H Or Hazmat Fees May Apply)

NETA PART: SIAL-Z0166-5MG

MFG.PART: Z0166-5MG

UNSPSC: 51180000

Manufacturer: Sigma-Aldrich

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Description

Product Name

α-Zearalenol,

assay

≥98% (HPLC)

Quality Level

200

form

powder

solubility

methanol: 9.80-10.20 mg/mL, clear, colorless to faintly yellow

storage temp.

−20°C

SMILES string

C[C@H]1CCC[C@H](O)CCC\C=C\c2cc(O)cc(O)c2C(=O)O1

InChI

1S/C18H24O5/c1-12-6-5-9-14(19)8-4-2-3-7-13-10-15(20)11-16(21)17(13)18(22)23-12/h3,7,10-12,14,19-21H,2,4-6,8-9H2,1H3/b7-3+/t12-,14+/m0/s1

InChI key

FPQFYIAXQDXNOR-QDKLYSGJSA-N

Gene Information

rat ... Ar(24208)

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Application

α-Zearalenol has been used:

as an analytical standard in the quantification of mycotoxins from animal feed[1]
to evaluate its oestrogenic activity on boar sperm motility [2], as an anti-oestrogen control in MCF7 cells[3]
as a reference standard in a liquid chromatography-negative ion electrospray tandem mass spectrometry with atmospheric pressure chemical ionization (LCAPCI/MS/MS) for bovine follicular fluids (FFs) quantification[4]

Biochem/physiol Actions

α-Zearalenol (α-ZOL) is a catabolite of zearalenone, synthesized majorly in granulosa cells, intestine and liver in pigs. It has estrogenic functionality.[5] α-ZOL inhibits sperm motility in horse possibly by eliciting genotoxic effect.[6] α-ZOL displays higher affinity towards estrogenic receptors.[7]

pictograms

GHS05,GHS08

signalword

Danger

hcodes

H314 - H351 - H361fd - H371 - H412

pcodes

P260 - P273 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338

Hazard Classifications

Aquatic Chronic 3 - Carc. 2 - Eye Dam. 1 - Repr. 2 - Skin Corr. 1B - STOT SE 2

Storage Class

8B - Non-combustible, corrosive hazardous materials

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c