Sigma-Aldrich Mouse Osteopontin. recombinant, expressed in NSO cells, powder, suitable for cell culture. 50 μg

Name: Sigma-Aldrich Mouse Osteopontin. recombinant, expressed in NSO cells, powder, suitable for cell culture. 50 μg
SKU: SIAL-O2260-50UG
Price: 401.74 USD

List Price $401.74 Your Price $401.74

Sigma-Aldrich Mouse Osteopontin. recombinant, expressed in NSO cells, powder, suitable for cell culture. 50 μg - SIAL (Additional S&H Or Hazmat Fees May Apply)

NETA PART: SIAL-O2260-50UG

MFG.PART: O2260-50UG

UNSPSC: 41122409

Manufacturer: Sigma-Aldrich

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Description

Product Name

Osteopontin from mouse, >95% (SDS-PAGE), recombinant, expressed in NSO cells, lyophilized powder, suitable for cell culture

biological source

mouse

Quality Level

100

recombinant

expressed in NSO cells

sterility

sterile

assay

>95% (SDS-PAGE)

form

lyophilized powder

mol wt

30 kDa by SDS-PAGE (reducing)
65 kDa by SDS-PAGE (reducing) (doublet)

packaging

pkg of 50 μg

technique(s)

cell culture | mammalian: suitable

Application

Osteopontin from mouse has been used:

to study its role in a mouse model of preterm brain injury[1]
as a positive control to analyze the relationship between the vascular calcification process and osteopontin (OPN) overexpression in the neointima of atherosclerotic plaques[2]
to study its interaction on the crystal growth process of hydroxyapatite in agarose hydrogels[3]

Biochem/physiol Actions

Osteopontin (OPN) is a secreted, highly acidic, calcium binding, phosphorylated glycoprotein that is chemotactic for macrophages, smooth muscle cells, endothelial cells and glial cells. In activated macrophages, OPN inhibits nitric oxide production and cytotoxicity.[4] Human, mouse, rat, pig and bovine OPN share 40% amino acid sequence identity.

Physical form

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline containing 2.5 mg bovine serum albumin.

Analysis Note

The biological activity is measured by its ability to mediate 293 cell adhesion.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c