Sigma-Aldrich Oligomycin. from Streptomyces diastatochromogenes, ≥90% total oligomycins basis (HPLC), powder, antibiotic. 100 mg

Name: Sigma-Aldrich Oligomycin. from Streptomyces diastatochromogenes, ≥90% total oligomycins basis (HPLC), powder, antibiotic. 100 mg
SKU: SIAL-O4876-100MG
Price: 1716.80 USD

List Price $1,716.80 Your Price $1,716.80

Sigma-Aldrich Oligomycin. from Streptomyces diastatochromogenes, ≥90% total oligomycins basis (HPLC), powder, antibiotic. 100 mg - SIAL (Additional S&H Or Hazmat Fees May Apply)

NETA PART: SIAL-O4876-100MG

MFG.PART: O4876-100MG

UNSPSC: 51102800

Manufacturer: Sigma-Aldrich

Skip to the end of the images gallery

Skip to the beginning of the images gallery

Description

Product Name

Oligomycin from Streptomyces diastatochromogenes, ≥90% total oligomycins basis (HPLC)

assay

≥90% total oligomycins basis (HPLC)

form

powder

antibiotic activity spectrum

fungi

mode of action

enzyme | inhibits

storage temp.

−20°C

InChI

1S/C45H74O11/c1-12-34-17-15-13-14-16-27(4)42(51)44(11,53)43(52)32(9)40(50)31(8)39(49)30(7)38(48)26(3)18-21-37(47)54-41-29(6)35(20-19-34)55-45(33(41)10)23-22-25(2)36(56-45)24-28(5)46/h13-15,17-18,21,25-36,38,40-42,46,48,50-51,53H,12,16,19-20,22-24H2,1-11H3/b14-13+,17-15-,21-18+

Inchi Key

MNULEGDCPYONBU-ZUSSGZTJSA-N

Looking for similar products? Visit Product Comparison Guide

General description

Chemical structure: macrolide

Application

Oligomycin from Streptomyces diastatochromogenes is used:

in the inhibition of mitochondrial ATP production Leigh syndrome (LS) cells.[1]
in ATP-linked respiration and maximal capacity respiration assay in astrocytes.[2]
in measurement of oxygen consumption rate (OCR) and extracellular acidification rates in breast cancer cell lines.[3]

Biochem/physiol Actions

Oligomycin belongs to the macrolide group of antibiotics.[4] It inhibits mitochondrial ATP-synthase enzyme and phosphoryl group transfer.[5] Oligomycin interacts with ATP synthase subunit-c in the Fo portion and impairs proton transport.[6]

Other Notes

2024 CiteAb Award Winner for Supplier Succeeding in Parkinson′s Research

A mixture of oligomycins A, B, and C.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c