Sigma-Aldrich Benzopyrene. ≥96% (HPLC). 1 g

Name: Sigma-Aldrich Benzoapyrene. ≥96% (HPLC). 1 g
SKU: SIAL-B1760-1G
Price: 584.64 USD

List Price $584.64 Your Price $584.64

Sigma-Aldrich Benzo[a]pyrene. ≥96% (HPLC). 1 g - SIAL (Additional S&H Or Hazmat Fees May Apply)

NETA PART: SIAL-B1760-1G

MFG.PART: B1760-1G

UNSPSC: 41116107

Manufacturer: Sigma-Aldrich

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Description

assay

≥96% (HPLC)

form

solid

bp

495 °C (lit.)

mp

177-180 °C (lit.)

SMILES string

c1ccc2c(c1)cc3ccc4cccc5ccc2c3c45

InChI

1S/C20H12/c1-2-7-17-15(4-1)12-16-9-8-13-5-3-6-14-10-11-18(17)20(16)19(13)14/h1-12H

InChI key

FMMWHPNWAFZXNH-UHFFFAOYSA-N

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Application

Benzo[a]pyrene (PAH), a polycyclic aromatic hydrocarbon pollutant, is used as a chemical carcinogen in experimental models of cancer. Carcinogenesis depends on it′s oxidation by CYP1A1 to benzo[a]pyrenediolepoxide, that forms depurinating adducts with DNA that dissociate to form abasic lesions. Benzo[a]pyrene is a ligand for the arylhydrocarbon receptor (AhR), and some of its biological effects, including the induction of CYP1A1, appear to be mediated via activation of the AhR.

pictograms

GHS08,GHS07,GHS09

signalword

Danger

hcodes

H317,H340,H350,H360FD,H410

pcodes

P202 - P261 - P273 - P280 - P302 + P352 - P308 + P313

Hazard Classifications

Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 1B - Muta. 1B - Repr. 1B - Skin Sens. 1

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c