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Sigma-Aldrich (±)-Mevalonolactone. ~97% (titration). 1 g
List Price $280.72 Your Price $280.72
Sigma-Aldrich (±)-Mevalonolactone. ~97% (titration). 1 g - SIAL (Additional S&H Or Hazmat Fees May Apply)
NETA PART: SIAL-M4667-1G
MFG.PART: M4667-1G
UNSPSC: 41122409
Manufacturer: Sigma-Aldrich
assay
~97% (titration)
storage temp.
−20°C
SMILES string
CC1(O)CCOC(=O)C1
InChI
1S/C6H10O3/c1-6(8)2-3-9-5(7)4-6/h8H,2-4H2,1H3
InChI key
JYVXNLLUYHCIIH-UHFFFAOYSA-N
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General description
Alkaline hydrolysis of mevalonolactone gives mevalonate.[1] Mevalonate is a precursor of farnesyl and geranylgeranyl pyrophosphates. These pyrophosphates are required for protein prenylation.[2]
Application
(±)-Mevalonolactone is used to:
- study the effect of statin on the prenylation of Ras and Rho GTPases[2]
- analyse the isoprenoid biosynthesis pathways in Listeria monocytogenes[3]
- study the the effects of statins on proliferation and migration of HUVECs (HGF-induced human umbilical vein endothelial cells)[4]
Other Notes
May also be liquid!
Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
flash_point_f
235.4 °F - closed cup
flash_point_c
113 °C - closed cup
PPE
Eyeshields, Gloves, type N95 (US)
| SKU | SIAL-M4667-1G |
|---|---|
| Supplier Part Number | M4667-1G |
| UM | EA |
| UNSPSC | 41122409 |
| Manufacturer | Sigma-Aldrich |
| Temperature | -20C |
| Refrigerated-Frozen | Y |
| ProductLine | SIAL |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 10.000000 |
| Lead Time | 9 |
| CAS Number | 674-26-0 |
| Energy Star | No |
| Green | No |
| Controlled | N |