Sigma-Aldrich mL-SA1. ≥95% (HPLC), powder, TRPML channel agonist. 25 mg

Name: Sigma-Aldrich mL-SA1. ≥95% (HPLC), powder, TRPML channel agonist. 25 mg
SKU: SIAL-SML0627-25MG
Price: 198.36 USD

List Price $198.36 Your Price $198.36

Sigma-Aldrich mL-SA1. ≥95% (HPLC), powder, TRPML channel agonist. 25 mg - SIAL (Additional S&H Or Hazmat Fees May Apply)

NETA PART: SIAL-SML0627-25MG

MFG.PART: SML0627-25MG

UNSPSC: 12352202

Manufacturer: Sigma-Aldrich

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Description

Product Name

mL-SA1, ≥95% (HPLC)

assay

≥95% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 5 mg/mL, clear (warmed)

storage temp.

2-8°C

SMILES string

N3(C(=O)c4c(cccc4)C3=O)CC(=O)N1C(CC(c2c1cccc2)C)(C)C

InChI

1S/C22H22N2O3/c1-14-12-22(2,3)24(18-11-7-6-8-15(14)18)19(25)13-23-20(26)16-9-4-5-10-17(16)21(23)27/h4-11,14H,12-13H2,1-3H3

InChI key

KDDHBJICVBONAX-UHFFFAOYSA-N

Application

mL-SA1 has been used as a transient receptor potential cation channel mucolipin 1 (TRPML1/ML1) agonist.[1]

Biochem/physiol Actions

mL-SA1 is a potent and selective cell permeable agonist of lysosomal mucolipin transient receptor potential channels (TRPML) 1, 2, 3 that significantly increases [Ca²⁺]cyt in HEK293 cells stably- or transiently-expressing mutant TRPML1 channels ML1-4A.

mL-SA1 is a potent and selective cell permeable agonist of lysosomal mucolipin transient receptor potential channels (TRPML) 1, 2, 3.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c