Sigma-Aldrich 4-Aminophthalhydrazide. ≥98% (HPLC), powder. 1 g

Name: Sigma-Aldrich 4-Aminophthalhydrazide. ≥98% (HPLC), powder. 1 g
SKU: SIAL-A8264-1G
Price: 199.52 USD

List Price $199.52 Your Price $199.52

Sigma-Aldrich 4-Aminophthalhydrazide. ≥98% (HPLC), powder. 1 g - SIAL (Additional S&H Or Hazmat Fees May Apply)

NETA PART: SIAL-A8264-1G

MFG.PART: A8264-1G

UNSPSC: 41122409

Manufacturer: Sigma-Aldrich

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Description

Product Name

4-Aminophthalhydrazide,

assay

≥98% (HPLC)

form

powder

mp

300 °C (lit.)

solubility

2 M NH₄OH: 50 mg/mL, clear to slightly hazy

SMILES string

Nc1ccc2C(=O)NNC(=O)c2c1

InChI

1S/C8H7N3O2/c9-4-1-2-5-6(3-4)8(13)11-10-7(5)12/h1-3H,9H2,(H,10,12)(H,11,13)

InChI key

HUDPLKWXRLNSPC-UHFFFAOYSA-N

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Related Categories

Detection Substrates & Enzymes

Protein Biology

Proteins & Enzymes

Application

4-Aminophthalhydrazide has been used in:

chemiluminescence-based reactive oxygen species (ROS) assay in bone marrow (BM) neutrophils post-Yersinia pseudotuberculosis infection[1]
neutrophil ROS assays post-K. pneumonia exposure[2]
neutrophil ROS assays in response to formylated-methionine-leucine-proline[3]

Biochem/physiol Actions

4-Aminophthalhydrazide or isoluminol is a chemiluminescent compound[4] that comprises a phthalazine ring. It is more hydrophilic than luminol.[5] Isoluminol is commercially used in a wide variety of in vitro immunoassays[4] and is a chemiluminescence amplifier for studying reactive oxygen species.[5] It is also useful as an electroluminescence (ECL) biosensor and as a probe for rapid microbial detection.[4]

Features and Benefits

Produces chemiluminescence.

pictograms

GHS07

signalword

Warning

hcodes

H315,H319,H335

pcodes

P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c