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Sigma-Aldrich Cyclophosphamide monohydrate. ISOPAC®. 1 g
List Price $194.88 Your Price $194.88
Sigma-Aldrich Cyclophosphamide monohydrate. ISOPAC®. 1 g - SIAL (Additional S&H Or Hazmat Fees May Apply)
NETA PART: SIAL-C7397-1G
MFG.PART: C7397-1G
UNSPSC: 12352100
Manufacturer: Sigma-Aldrich
assay
97.0-103.0% (HPLC)
form
powder
mp
49-51 °C (lit.)
storage temp.
2-8°C
SMILES string
[H]O[H].ClCCN(CCCl)P1(=O)NCCCO1
InChI
1S/C7H15Cl2N2O2P.H2O/C8-2-5-11(6-3-9)14(12)10-4-1-7-13-14;/h1-7H2,(H,10,12);1H2
Inchi Key
PWOQRKCAHTVFLB-UHFFFAOYSA-N
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Application
Cyclophosphamide, a nitrogen mustard DNA alkylating agent, is used to study its mechanisms of action as an anticancer and antiimmunity drug.
Biochem/physiol Actions
Cyclophosphamide is a cytotoxic nitrogen mustard derivative widely used in cancer chemotherapy. It cross-links DNA, causes strand breakage, and induces mutations. Its clinical activity is associated with a decrease in aldehyde dehydrogenase 1 (ALDH1) activity.
Cytotoxic nitrogen mustard derivative widely used in cancer chemotherapy. It cross-links DNA, causes strand breakage, and induces mutations.
Packaging
Packaged in a 100 mL serum bottle with silicon/PTFE septum and aluminum tear seal.
Preparation Note
Dissolving the contents in 100 mL of solvent yields a 1% solution.
Legal Information
Isopac is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Injecting a compatible solvent directly into the vial permits preparation of any desired strength solution without exposure.
pictograms
GHS06,GHS08
signalword
Danger
hcodes
H301,H340,H350,H360FD
pcodes
P202 - P264 - P280 - P301 + P310 - P405 - P501
Hazard Classifications
Acute Tox. 3 Oral - Carc. 1B - Muta. 1B - Repr. 1A
Storage Class
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk_germany
WGK 3
PPE
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
| SKU | SIAL-C7397-1G |
|---|---|
| Supplier Part Number | C7397-1G |
| UM | EA |
| UNSPSC | 12352100 |
| Manufacturer | Sigma-Aldrich |
| Temperature | 2-8C |
| Refrigerated-Frozen | Y |
| ProductLine | SIAL |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 10.000000 |
| Lead Time | 9 |
| CAS Number | 6055-19-2 |
| Energy Star | No |
| Green | No |
| Controlled | N |