Cayman Calyculin A, 25 µg

Name: Cayman Calyculin A, 25 µg
SKU: CAYM-19246-25
Price: 643.00 USD

List Price $643.00 Your Price $643.00

Cayman Calyculin A, 25 µg-CAYM (Additional S&H Or Hazmat Fees May Apply)

NETA PART: CAYM-19246-25

MFG.PART: 19246-25

UNSPSC: 12352203

Manufacturer: Cayman

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Description

Product Description

Calyculin A is a natural, cell-permeable inhibitor of the serine-threonine protein phosphatases (PP) PP1 and PP2A (IC₅₀s = 0.3-0.7 and 0.5-1 nM, respectively).^1,2,3 It is without significant effect against PP2B, PP2C, and PP4.² Through its effects on PP1 and PP2A, calyculin A has been shown to either promote or inhibit cancer cell growth in tumor cell lines and animal models.^4,5

WARNING This product is not for human or veterinary use.

Technical Information

Formal Name	N-[(3S)-3-[4-[(1E)-3-[(2R,3R,5R,7S,8S,9R)-2-[(1S,3S,4S,5R,6R,7E,9E,11E,13Z)-14-cyano-3,5-dihydroxy-1-methoxy-4,6,8,9,13-pentamethyl-7,9,11,13-tetradecatetraen-1-yl]-9-hydroxy-4,4,8-trimethyl-3-(phosphonooxy)-1,6-dioxaspiro[4.5]dec-7-yl]-1-propen-1-yl]-2-oxazolyl]butyl]-4-deoxy-4-(dimethylamino)-5-O-methyl-L-ribonamide
CAS Number	101932-71-2
Synonyms	(−)-Calyculin A
Molecular Formula	C₅₀H₈₁N₄O₁₅P
Formula Weight	1009.2
Purity	≥98%
Formulation	A solid
Solubility(Learn about Variance in Solubility)	DMSO: SolubleEthanol: Soluble
SMILES	C[C@H]1[C@H](O)C[C@@]2(C(C)(C)[C@@H](OP(O)(O)=O)[C@]([C@@H](OC)C[C@H](O)[C@H](C)[C@H](O)[C@H](C)/C=C(C)/C(C)=C/C=C/C(C)=C\C#N)([H])O2)O[C@H]1C/C=C/C3=COC([C@H](CCNC([C@@H](O)[C@@H](O)[C@@H](N(C)C)COC)=O)C)=N3
InChi Code	InChI=1S/C50H81N4O15P/c1-29(20-22-51)16-14-17-30(2)32(4)24-33(5)42(57)35(7)38(55)25-41(65-13)45-46(69-70(61,62)63)49(8,9)50(68-45)26-39(56)34(6)40(67-50)19-15-18-36-27-66-48(53-36)31(3)21-23-52-47(60)44(59)43(58)37(28-64-12)54(10)11/h14-18,20,24,27,3
InChi Key	FKAWLXNLHHIHLA-YCBIHMBMSA-N
Origin	Animal/Discodermia calyx

Shipping & Storage Information

Storage	-20°C
Shipping	Room temperature in continental US; may vary elsewhere
Stability	≥ 4 years

Specifications

More Information
SKU	CAYM-19246-25
Supplier Part Number	19246-25
UM	EA
UNSPSC	12352203
Manufacturer	Cayman
Temperature	-20
Refrigerated-Frozen	Y
CountryOfOrigin	United States
ProductLine	CAYM
Qty	1
MinOrderQty	1
Weight	7.000000
Lead Time	5
Hazardous	Y
CAS Number	101932-71-2
Energy Star	No
Green	No
Controlled	N

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NETA PART NO.	Quantity

Cayman Calyculin A, 25 µg

Product Description

Technical Information

Shipping & Storage Information

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