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Cayman Tolvaptan-d7, 2.5 mg
List Price $362.00 Your Price $362.00
Cayman Tolvaptan-d7, 2.5 mg-CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-26453-25
MFG.PART: 26453-25
UNSPSC: 41116113
Manufacturer: Cayman
Product Description
Tolvaptan-d7 is intended for use as an internal standard for the quantification of tolvaptan (Item No. 19691) by GC- or LC-MS. Tolvaptan is a nonpeptide vasopressin V2 receptor antagonist (IC50 = 3 nM for rat receptor) and a diuretic agent.1 It is selective for V2 over V1 receptors (IC50 = 0.58 μM). Tolvaptan increases urine volume by 3-fold in rats when administered at a dose of 0.54 mg/kg. It also reduces left ventricular end-systolic volumes and improves left ventricular ejection fraction in a rat model of myocardial infarction.2 Formulations containing tolvaptan have been used to treat hyponatremia.
WARNING This product is not for human or veterinary use.
Technical Information
| Formal Name | N-[4-[(7- |
| CAS Number | 1246818-18-7 |
| Molecular Formula | C26H18ClD7N2O3 |
| Formula Weight | 456.0 |
| Purity | ≥99% deuterated forms (d1-d7) |
| Formulation | A solid |
| Solubility(Learn about Variance in Solubility) | DMSO: Slightly solubleMethanol: Slightly soluble |
| SMILES | O=C(NC1=CC(C)=C(C(N2C(C=CC(Cl)=C3)=C3C(O)CCC2)=O)C=C1)C4=C(C([2H])([2H])[2H])C([2H])=C([2H])C([2H])=C4[2H] |
| InChi Code | InChI=1S/C26H25ClN2O3/c1-16-6-3-4-7-20(16)25(31)28-19-10-11-21(17(2)14-19)26(32)29-13-5-8-24(30)22-15-18(27)9-12-23(22)29/h3-4,6-7,9-12,14-15,24,30H,5,8,13H2,1-2H3,(H,28,31)/i1D3,3D,4D,6D,7D |
| InChi Key | GYHCTFXIZSNGJT-FFQSSJIFSA-N |
| Origin | Synthetic |
Shipping & Storage Information
| Storage | -20°C |
| Shipping | Wet ice in continental US; may vary elsewhere |
| Stability | ≥ 4 years |
| SKU | CAYM-26453-25 |
|---|---|
| Supplier Part Number | 26453-25 |
| UM | EA |
| UNSPSC | 41116113 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | Canada |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 1246818-18-7 |
| Energy Star | No |
| Green | No |
| Controlled | N |