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Cayman ng,ng-dimethyl-L-Arginine-d6 (hydrochloride), 5 mg
List Price
$537.00
Your Price
$537.00
Cayman ng,ng-dimethyl-L-Arginine-d6 (hydrochloride), 5 mg-CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-33266-5
MFG.PART:
33266-5
UNSPSC:
41105505
Manufacturer:
Cayman
Product Description
Ng,Ng-dimethyl-L-arginine-d6 (ADMA-d6) (hydrochloride) is intended for use as an internal standard for the quantification of Ng,Ng-dimethyl-L-arginine (Item No. 80230) by GC- or LC-MS. ADMA is an endogenous inhibitor of nitric oxide synthase (NOS).1,2 It is formed from arginine by protein arginine methyltransferases (PRMTs) and degraded by dimethylarginine dimethylaminohydrolases (DDAHs) and alanine-glyoxylate aminotransferase 2 (AGXT2).1 ADMA levels are increased concomitant with an increase in blood pressure in Dahl salt-sensitive rats fed a high-salt diet.2 ADMA levels are increased in the plasma in a variety of endothelial dysfunction-related diseases, including hypertension, congestive heart failure, and end-stage renal disease.1,3,4
WARNING This product is not for human or veterinary use.
Technical Information
| Formal Name | N5- |
| CAS Number | 1313730-20-9 |
| Synonyms |
|
| Molecular Formula | C8H12D6N4O2 • 2HCl |
| Formula Weight | 281.2 |
| Purity | ≥99% deuterated forms (d1-d6) |
| Formulation(Request formulation change) | A solid |
| Solubility(Learn about Variance in Solubility) | DMSO: Sparingly soluble: 1-10 mg/mLPBS pH 7.2: Soluble: ≥10 mg/mL |
| SMILES | [2H]C([2H])([2H])N(C([2H])([2H])[2H])C(NCCC[C@H](N)C(O)=O)=N.Cl.Cl |
| InChi Code | InChI=1S/C8H18N4O2.2ClH/c1-12(2)8(10)11-5-3-4-6(9)7(13)14;;/h6H,3-5,9H2,1-2H3,(H2,10,11)(H,13,14);2*1H/t6-;;/m0../s1/i1D3,2D3;; |
| InChi Key | SYLNVYJOPZWPJI-WTPXGJEESA-N |
Shipping & Storage Information
| Storage | -20°C |
| Shipping | Room temperature in continental US; may vary elsewhere |
| Stability | ≥ 4 years |
| SKU | CAYM-33266-5 |
|---|---|
| Supplier Part Number | 33266-5 |
| UM | EA |
| UNSPSC | 41105505 |
| Manufacturer | Cayman |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 1313730-20-9 |
| Energy Star | No |
| Green | No |
| Controlled | N |