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Cayman Oleacein, 5 mg
List Price
$358.00
Your Price
$358.00
Cayman Oleacein, 5 mg-CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-40719-5
MFG.PART:
40719-5
UNSPSC:
41106300
Manufacturer:
Cayman
Product Description
Oleacein is a secoiridoid polyphenol that has been found in O. europea and has diverse biological activities.1,2,3,4 It inhibits 5-lipoxygenase (5-LO; IC50 = 2 µM for the human enzyme).1 Oleacein (20 and 50 µM) reduces lipid accumulation and inhibits the transition into foam cells in human monocyte-derived macrophages.2 It decreases lipid accumulation and levels of peroxisome proliferator-activated receptor γ (PPARγ) and fatty acid synthase (FASN), as well as increases adiponectin levels, in 3T3-L1 adipocytes.3 In vivo, oleacein (20 mg/kg) reduces macrophage and lymphocyte infiltration in abdominal fat tissue and adipocyte size in a mouse model of high-fat diet-induced obesity. Oleacein also delays disease onset and progression in a mouse model of experimental autoimmune encephalomyelitis (EAE).4
WARNING This product is not for human or veterinary use.
Technical Information
| Formal Name | (3S,4E)-4-formyl-3- |
| CAS Number | 149183-75-5 |
| Molecular Formula | C17H20O6 |
| Formula Weight | 320.3 |
| Purity | ≥90% |
| Formulation | A neat oil |
| Solubility(Learn about Variance in Solubility) | Acetonitrile: SolubleDMSO: Soluble |
| SMILES | O=CC[C@H](/C(C=O)=C\C)CC(OCCC1=CC(O)=C(O)C=C1)=O |
| InChi Code | InChI=1S/C17H20O6/c1-2-13(11-19)14(5-7-18)10-17(22)23-8-6-12-3-4-15(20)16(21)9-12/h2-4,7,9,11,14,20-21H,5-6,8,10H2,1H3/b13-2-/t14-/m0/s1 |
| InChi Key | XLPXUPOZUYGVPD-VMPILDALSA-N |
| Origin | Plant/Olea europaea |
Shipping & Storage Information
| Storage | -20°C |
| Shipping | Wet ice in continental US; may vary elsewhere |
| Stability | ≥ 4 years |
| SKU | CAYM-40719-5 |
|---|---|
| Supplier Part Number | 40719-5 |
| UM | EA |
| UNSPSC | 41106300 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | Switzerland |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 149183-75-5 |
| Energy Star | No |
| Green | No |
| Controlled | N |