We use cookies to make your experience better. To comply with the new e-Privacy directive, we need to ask for your consent to set the cookies. Learn about our cookie policy.
Cayman Pyrazofurin, 1 mg
List Price
$65.00
Your Price
$65.00
Cayman Pyrazofurin, 1 mg-CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-43569-1
MFG.PART:
43569-1
UNSPSC:
41116107
Manufacturer:
Cayman
Product Description
Pyrazofurin is a nucleoside derivative that has been found in S. candidus and has antiviral and anticancer activities.1,2,3 It is an inhibitor of orotidine-5’-monophosphate decarboxylase (OMP decarboxylase) that inhibits DNA synthesis.2 Pyrazofurin inhibits the cytopathic effect of parainfluenza-3 virus, measles virus, vaccinia virus, and herpes simplex virus 2 (HSV-2) in Vero cells (EC50s = 3, 9.6, 2.8, and 20 µM, respectively).1 It also reduces infection of Calu-3 cells by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) with a synergistic effect when used in combination with molnupiravir (Item No. 29586) or remdesivir (Item No. 30354).3 Pyrazofurin reduces tumor growth in L1210 and P388 leukemia, Lewis lung, and B16 murine melanoma models (ID50s = 3.2, 3.3, 1.8, and 63 nM, respectively).1
WARNING This product is not for human or veterinary use.
Technical Information
| Formal Name | 4-hydroxy-3-β-D- |
| CAS Number | 30868-30-5 |
| Molecular Formula | C9H13N3O6 |
| Formula Weight | 259.2 |
| Purity | ≥95% |
| Formulation(Request formulation change) | A solid |
| Solubility(Learn about Variance in Solubility) | DMSO: Sparingly soluble: 1-10 mg/mLPBS (pH 7.2): Sparingly soluble: 1-10 mg/mL |
| SMILES | OC1=C(C(N)=O)NN=C1[C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O |
| InChi Code | InChI=1S/C9H13N3O6/c10-9(17)4-6(15)3(11-12-4)8-7(16)5(14)2(1-13)18-8/h2,5,7-8,13-16H,1H2,(H2,10,17)(H,11,12)/t2-,5-,7-,8+/m1/s1 |
| InChi Key | XESARGFCSKSFID-FLLFQEBCSA-N |
Shipping & Storage Information
| Storage | -20°C |
| Shipping | Room temperature in continental US; may vary elsewhere |
| Stability | ≥ 4 years |
| SKU | CAYM-43569-1 |
|---|---|
| Supplier Part Number | 43569-1 |
| UM | EA |
| UNSPSC | 41116107 |
| Manufacturer | Cayman |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | China |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 30868-30-5 |
| Energy Star | No |
| Green | No |
| Controlled | N |