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Cayman BCMA/CD269 Polyclonal Antibody, 100 µl
List Price
$293.00
Your Price
$293.00
Cayman BCMA/CD269 Polyclonal Antibody, 100 µl-CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-43761-100
MFG.PART:
43761-100
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
B cell maturation antigen (BCMA), also known as CD269, is a member of the TNF receptor superfamily.1 It is composed of an extracellular domain, a transmembrane region, and a cytoplasmic domain.1,2 BCMA is found in the cell membrane of late memory B cells and recognizes TNF superfamily member 13B (TNFSF13B), also known as B cell activating factor (BAFF), and a proliferation-inducing ligand (APRIL), which both promote B cell survival and differentiation into short- or long-lived plasma cells, antibody production, and immunoglobulin class switching.1,3 The extracellular domain of BCMA can cleaved by γ-secretase to release soluble BCMA (sBCMA), which can bind APRIL and prevent APRIL-induced signaling in B cells, reducing B cell survival.2 Increased sBCMA levels are associated with lower progression-free- and overall survival in patients with multiple myeloma.4 Caymans BCMA/CD269 Polyclonal Antibody can be used for ELISA.
WARNING This product is not for human or veterinary use.
Technical Information
| Synonyms |
|
| Immunogen | Recombinant human BCMA |
| Formulation(Request formulation change) | 20 or 100 µl of protein A-affinity purified polyclonal antibody |
| Storage Buffer | 0.2 μm filtered solution in PBS |
| Host | Rabbit |
| Isotype | IgG |
| Applications | ELISA |
| Cross Reactivity | (+) BCMA |
| Species Reactivity | (+) Human |
Shipping & Storage Information
| Storage | -80°C |
| Shipping | Dry ice in continental US; may vary elsewhere |
| Stability | ≥ 1 year |
| SKU | CAYM-43761-100 |
|---|---|
| Supplier Part Number | 43761-100 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| Temperature | -80 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| Energy Star | No |
| Green | No |
| Controlled | N |