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Cayman GR83074 (trifluoroacetate salt), 1 mg
List Price
$109.00
Your Price
$109.00
Cayman GR83074 (trifluoroacetate salt), 1 mg-CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-44017-1
MFG.PART:
44017-1
UNSPSC:
12352107
Manufacturer:
Cayman
Product Description
GR83074 is a peptide antagonist of the neurokinin-2 (NK2) receptor.1 It selectively inhibits neurokinin A-induced contractions in rat colon muscularis mucosae, which express NK2 receptors, over substance P-induced contractions in guinea pig ileum longitudinal smooth muscle strips, which express NK1 receptors (pKbs = 8.2 and 5.8, respectively). GR83074 (0.3 µmol/kg) inhibits neurokinin A-induced bronchoconstriction in guinea pigs.
WARNING This product is not for human or veterinary use.
Technical Information
| Formal Name | N2-[(1,1-dimethyl |
| Synonyms |
|
| Molecular Formula | C50H72N12O9 • XCF3COOH |
| Formula Weight | 985.2 |
| Purity | ≥95% |
| Formulation(Request formulation change) | A solid |
| Peptide Sequence | Boc-RAwFpPX-NH2 (X = norisoleucine) |
| Solubility(Learn about Variance in Solubility) | DMSO: Slightly soluble: 0.1-1 mg/mLWater: Slightly soluble: 0.1-1 mg/mL |
| SMILES | O=C(N1[C@H](CCC1)C(N2[C@@H](CCC2)C(N[C@H](C(N)=O)CCCC)=O)=O)[C@H](CC3=CC=CC=C3)NC([C@H](NC([C@H](C)NC([C@H](CCCNC(N)=N)NC(OC(C)(C)C)=O)=O)=O)CC4=CNC5=CC=CC=C45)=O.FC(F)(C(O)=O)F |
| InChi Code | InChI=1S/C50H72N12O9.C2HF3O2/c1-6-7-19-35(41(51)63)57-45(67)39-22-14-25-61(39)47(69)40-23-15-26-62(40)46(68)38(27-31-16-9-8-10-17-31)59-44(66)37(28-32-29-55-34-20-12-11-18-33(32)34)58-42(64)30(2)56-43(65)36(21-13-24-54-48(52)53)60-49(70)71-50(3,4)5;3-2(4,5)1(6)7/h8-12,16-18,20,29-30,35-40,55H,6-7,13-15,19,21-28H2,1-5H3,(H2,51,63)(H,56,65)(H,57,67)(H,58,64)(H,59,66)(H,60,70)(H4,52,53,54);(H,6,7)/t30-,35-,36-,37+,38-,39-,40+;/m0./s1 |
| InChi Key | IRCAIGPCPMZDKO-FFWYJSDESA-N |
Shipping & Storage Information
| Storage | -20°C |
| Shipping | Room temperature in continental US; may vary elsewhere |
| Stability | ≥ 4 years |
| SKU | CAYM-44017-1 |
|---|---|
| Supplier Part Number | 44017-1 |
| UM | EA |
| UNSPSC | 12352107 |
| Manufacturer | Cayman |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| Energy Star | No |
| Green | No |
| Controlled | N |