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Cayman Lipid C16-C, 1 mg
List Price $116.00 Your Price $116.00
Cayman Lipid C16-C, 1 mg-CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-44085-1
MFG.PART: 44085-1
UNSPSC: 12352202
Manufacturer: Cayman
Product Description
Lipid C16-C is an ionizable cationic lipid that has been used in the generation of lipid nanoparticles (LNPs) for the delivery of mRNA in vitro and in vivo.1 LNPs containing lipid C16-C selectively traffic to mouse liver and spleen over the lungs, kidneys, lymph nodes, and heart. LNPs containing lipid C16-C and encapsulating mRNA encoding HER2-targeting chimeric antigen receptor (CAR) induce CAR expression in human macrophages ex vivo and induce cytotoxicity in HER2-expressing SKOV3 ovarian cancer cells in vitro.
WARNING This product is not for human or veterinary use.
Technical Information
| Formal Name | 17-(2-(4-(2-(2-(2-(bis(2-hydroxyhexadecyl)amino)ethoxy)ethoxy)ethyl)piperazin-1-yl)ethyl)-26-(2-hydroxyhexadecyl)-20,23-dioxa-17,26-diazadotetracontane-15,28-diol |
| CAS Number | 2639634-86-7 |
| Molecular Formula | C98H201N5O9 |
| Formula Weight | 1593.7 |
| Purity | ≥95% |
| Formulation(Request formulation change) | A 10 mg/mL solution in ethanol |
| Solubility(Learn about Variance in Solubility) | Ethanol: Soluble: ≥10 mg/mL |
| SMILES | OC(CN(CCOCCOCCN(CC(CCCCCCCCCCCCCC)O)CC(CCCCCCCCCCCCCC)O)CCN1CCN(CC1)CCOCCOCCN(CC(CCCCCCCCCCCCCC)O)CC(CCCCCCCCCCCCCC)O)CCCCCCCCCCCCCC |
| InChi Code | InChI=1S/C98H201N5O9/c1-6-11-16-21-26-31-36-41-46-51-56-61-66-94(104)89-101(78-82-110-86-88-112-84-80-103(92-97(107)69-64-59-54-49-44-39-34-29-24-19-14-9-4)93-98(108)70-65-60-55-50-45-40-35-30-25-20-15-10-5)76-75-99-71-73-100(74-72-99)77-81-109-85-87-111-83-79-102(90-95(105)67-62-57-52-47-42-37-32-27-22-17-12-7-2)91-96(106)68-63-58-53-48-43-38-33-28-23-18-13-8-3/h94-98,104-108H,6-93H2,1-5H3 |
| InChi Key | AFXLHIXDLDFTAT-UHFFFAOYSA-N |
Shipping & Storage Information
| Storage | -20°C |
| Shipping | Room temperature in continental US; may vary elsewhere |
| Stability | ≥ 2 years |
| SKU | CAYM-44085-1 |
|---|---|
| Supplier Part Number | 44085-1 |
| UM | EA |
| UNSPSC | 12352202 |
| Manufacturer | Cayman |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | Y |
| CAS Number | 2639634-86-7 |
| Energy Star | No |
| Green | No |
| Controlled | N |