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Cayman Deoxyshikonin, 1 mg
Product Description
Deoxyshikonin is a naphthoquinone that has been found in L. erythrorhizon and has diverse biological activities.1,2,3,4 It is active against H. pylori strains in vitro (MIC = 0.5-1 µg/mL) and reduces H. pylori colonization of gastric mucosa in mice when administered at a dose of 7 mg/kg.1 Deoxyshikonin (10-40 µM) inhibits rotavirus replication and inhibits rotavirus-induced autophagy in Caco-2 cells.2 In vivo, deoxyshikonin (5 and 10 mg/kg) increases body weight and survival and reduces diarrhea score in rotavirus-infected mice. Topical application of deoxyshikonin (3 and 20 µM) increases wound closure percentage in a model of diabetic wound healing using rats with streptozotocin-induced diabetes.3 Topical application of deoxyshikonin (0.5 mm) increases hair growth in depilated mice.4
WARNING This product is not for human or veterinary use.
Technical Information
| Formal Name | 5,8-dihydroxy- |
| CAS Number | 43043-74-9 |
| Synonyms |
|
| Molecular Formula | C16H16O4 |
| Formula Weight | 272.3 |
| Purity | ≥98% |
| Formulation(Request formulation change) | A solid |
| Solubility(Learn about Variance in Solubility) | DMSO: Slightly soluble: 0.1-1 mg/mLEthanol: Slightly soluble: 0.1-1 mg/mL |
| SMILES | O=C1C=C(CC/C=C(C)/C)C(C2=C1C(O)=CC=C2O)=O |
| InChi Code | InChI=1S/C16H16O4/c1-9(2)4-3-5-10-8-13(19)14-11(17)6-7-12(18)15(14)16(10)20/h4,6-8,17-18H,3,5H2,1-2H3 |
| InChi Key | VOMDIEGPEURZJO-UHFFFAOYSA-N |
| Origin | Plant/Lithospermum erythrorhizon (Siebold & Zucc.) |
Shipping & Storage Information
| Storage | -20°C |
| Shipping | Room temperature in continental US; may vary elsewhere |
| Stability | ≥ 4 years |
| SKU | CAYM-44092-1 |
|---|---|
| Supplier Part Number | 44092-1 |
| UM | EA |
| UNSPSC | 12352107 |
| Manufacturer | Cayman |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | China |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 43043-74-9 |
| Energy Star | No |
| Green | No |
| Controlled | N |