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Cayman DS12881479, 1 mg
List Price $127.00 Your Price $127.00
Cayman DS12881479, 1 mg-CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-44121-1
MFG.PART: 44121-1
UNSPSC: 41122409
Manufacturer: Cayman
Product Description
DS12881479 is an inhibitor of MAP kinase-interacting serine/threonine protein kinase 1 (MNK1; IC50s = 21 and 416 nM for the inactive and active forms, respectively).1 It is selective for MNK1 over 46 other kinases but does inhibit FMS-related tyrosine kinase 3 (FLT3) and dual-specificity tyrosine phosphorylation-regulated kinase 1A (DYRK1A) at 5 µM.
WARNING This product is not for human or veterinary use.
Technical Information
| Formal Name | 1-methyl-N-(5- |
| CAS Number | 2373065-59-7 |
| Molecular Formula | C16H19N3OS |
| Formula Weight | 301.4 |
| Purity | ≥98% |
| Formulation(Request formulation change) | A solid |
| Solubility(Learn about Variance in Solubility) | DMSO: Soluble: ≥ 10 mg/mLEthanol: Sparingly soluble: 1-10 mg/mL |
| SMILES | CN1CCC(C(NC(S2)=NC=C2C3=CC=CC=C3)=O)CC1 |
| InChi Code | InChI=1S/C16H19N3OS/c1-19-9-7-13(8-10-19)15(20)18-16-17-11-14(21-16)12-5-3-2-4-6-12/h2-6,11,13H,7-10H2,1H3,(H,17,18,20) |
| InChi Key | BTZKRRFKIKIADV-UHFFFAOYSA-N |
Shipping & Storage Information
| Storage | -20°C |
| Shipping | Room temperature in continental US; may vary elsewhere |
| Stability | ≥ 4 years |
| SKU | CAYM-44121-1 |
|---|---|
| Supplier Part Number | 44121-1 |
| UM | EA |
| UNSPSC | 41122409 |
| Manufacturer | Cayman |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | China |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 2373065-59-7 |
| Energy Star | No |
| Green | No |
| Controlled | N |