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Cayman CF3-2N6-UC18, 1 mg
List Price $65.00 Your Price $65.00
Cayman CF3-2N6-UC18, 1 mg-CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-44140-1
MFG.PART: 44140-1
UNSPSC: 12352202
Manufacturer: Cayman
Product Description
CF3-2N6-UC18 is an ionizable cationic and chloroquine-derived lipid that has been used in the generation of lipid nanoparticles (LNPs) for the delivery of mRNA in vitro and in vivo.1 LNPs containing CF3-2N6-UC18 and encapsulating a Cy5-mRNA reporter exhibit increased cellular uptake via micropinocytosis and improved endosomal escape compared with LNPs containing non-chloroquine-derived lipids. LNPs containing CF3-2N6-UC18 selectively accumulate in mouse lymph nodes after intravenous administration.
WARNING This product is not for human or veterinary use.
Technical Information
| Formal Name | N1,N1-di-9-octa |
| CAS Number | 3042854-95-2 |
| Molecular Formula | C52H88F3N3 |
| Formula Weight | 812.3 |
| Purity | ≥90% |
| Formulation(Request formulation change) | A neat oil |
| Solubility(Learn about Variance in Solubility) | Ethanol: Soluble: ≥10 mg/mL |
| SMILES | CCCCCCCC/C=C\CCCCCCCCN(CCCCCCCC/C=C\CCCCCCCC)CCCCCCNC1=C(C=CC(C(F)(F)F)=C2)C2=NC=C1 |
| InChi Code | InChI=1S/C52H88F3N3/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-32-36-44-58(45-37-33-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2)46-38-34-31-35-42-56-50-41-43-57-51-47-48(52(53,54)55)39-40-49(50)51/h17-20,39-41,43,47H,3-16,21-38,42,44-46H2,1-2H3,(H,56,57)/b19-17-,20-18- |
| InChi Key | RQICHMVWIDRVQC-CLFAGFIQSA-N |
Shipping & Storage Information
| Storage | -20°C |
| Shipping | Room temperature in continental US; may vary elsewhere |
| Stability | ≥ 2 years |
| SKU | CAYM-44140-1 |
|---|---|
| Supplier Part Number | 44140-1 |
| UM | EA |
| UNSPSC | 12352202 |
| Manufacturer | Cayman |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | China |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | Y |
| CAS Number | 3042854-95-2 |
| Energy Star | No |
| Green | No |
| Controlled | N |