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Cayman Diclofenac (epolamine), 10 mg
Product Description
Diclofenac is a non-steroidal anti-inflammatory drug (NSAID) and COX inhibitor (IC50s = 0.9-2.7 and 1.5-20 µM, for human COX-1 and COX-2, respectively).1,2 It is also an active metabolite of diclofenac methyl ester (Item No. 22218) and diclofenac amide (Item No. 21969).3,4 Diclofenac inhibits release of arachidonic acid (Item Nos. 90010 | 90010.1 | 10006607) induced by A23187 (Item No. 11016) in isolated rat peritoneal neutrophils and macrophages (IC50s = 60 and 10 µM, respectively).5 Transdermal administration of diclofenac inhibits carrageenan-induced paw edema in rats.6 Formulations containing diclofenac have been used in the treatment of pain associated with osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis.
WARNING This product is not for human or veterinary use.
Technical Information
| Formal Name | 2-[(2,6-dichloro |
| CAS Number | 119623-66-4 |
| Molecular Formula | C14H11Cl2NO2 • C6H13NO |
| Formula Weight | 411.3 |
| Purity | ≥98% |
| Formulation(Request formulation change) | A solid |
| Solubility(Learn about Variance in Solubility) | DMSO: Soluble: ≥10 mg/mLEthanol: Soluble: ≥10 mg/mLPBS pH 7.2: Sparingly soluble: 1-10 mg/mL |
| SMILES | O=C(CC1=C(NC2=C(Cl)C=CC=C2Cl)C=CC=C1)O.OCCN3CCCC3 |
| InChi Code | InChI=1S/C14H11Cl2NO2.C6H13NO/c15-10-5-3-6-11(16)14(10)17-12-7-2-1-4-9(12)8-13(18)19;8-6-5-7-3-1-2-4-7/h1-7,17H,8H2,(H,18,19);8H,1-6H2 |
| InChi Key | DCERVXIINVUMKU-UHFFFAOYSA-N |
Shipping & Storage Information
| Storage | -20°C |
| Shipping | Room temperature in continental US; may vary elsewhere |
| Stability | ≥ 4 years |
| SKU | CAYM-44224-10 |
|---|---|
| Supplier Part Number | 44224-10 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | China |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | Y |
| CAS Number | 119623-66-4 |
| Energy Star | No |
| Green | No |
| Controlled | N |