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Cayman Mafenide (acetate), 1 g
List Price
$262.00
Your Price
$262.00
Cayman Mafenide (acetate), 1 g-CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-44225-1
MFG.PART:
44225-1
UNSPSC:
12352107
Manufacturer:
Cayman
Product Description
Mafenide is a sulfonamide antibiotic.1,2 It is active against clinical isolates of S. pyogenes, methicillin-susceptible S. aureus (MSSA), methicillin-resistant S. aureus (MRSA), Enterococcus, Enterobacteriaceae, and Gram-negative bacilli from burn patients in an agar well diffusion assay (mean zone of inhibition = 24-37 mm) but not in a broth dilution assay with MIC values ranging from 250 to greater than 5,000 μg/mL.1 Mafenide is also active against clinical isolates of K. pneumoniae that produce extended spectrum β-lactamase (ESBL), P. aeruginosa, and A. baumannii-calcoaceticus from burn patients in an agar well diffusion assay (mean zones of inhibition = 23.5, 28.9, and 25.8 mm, respectively) but not in a broth dilution assay (mean MICs = 1,024 μg/mL for all).2 It decreases mortality in a rat model of burn wounds seeded with rat virulent P. aeruginosa.3 Mafenide also inhibits human carbonic anhydrase I (CAI) and CAII (Kis = 41.91 and 0.612 μM, respectively).4 Formulations containing mafenide have been used in the treatment of bacterial infections associated with burn wounds.
WARNING This product is not for human or veterinary use.
Technical Information
| Formal Name | 4-(aminomethyl)-benzenesulfonamide, monoacetate |
| CAS Number | 13009-99-9 |
| Synonyms |
|
| Molecular Formula | C7H10N2O2S • C2H4O2 |
| Formula Weight | 246.3 |
| Purity | ≥98% |
| Formulation(Request formulation change) | A solid |
| Solubility(Learn about Variance in Solubility) | DMSO: Sparingly soluble: 1-10 mg/mLPBS pH 7.2: Soluble: ≥10 mg/mL |
| SMILES | O=C(C)O.NCC1=CC=C(S(N)(=O)=O)C=C1 |
| InChi Code | InChI=1S/C7H10N2O2S.C2H4O2/C8-5-6-1-3-7(4-2-6)12(9,10)11;1-2(3)4/h1-4H,5,8H2,(H2,9,10,11);1H3,(H,3,4) |
| InChi Key | UILOTUUZKGTYFQ-UHFFFAOYSA-N |
Shipping & Storage Information
| Storage | -20°C |
| Shipping | Room temperature in continental US; may vary elsewhere |
| Stability | ≥ 4 years |
| SKU | CAYM-44225-1 |
|---|---|
| Supplier Part Number | 44225-1 |
| UM | EA |
| UNSPSC | 12352107 |
| Manufacturer | Cayman |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | China |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 13009-99-9 |
| Energy Star | No |
| Green | No |
| Controlled | N |