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Cayman Odiparcil, 1 mg
Product Description
Odiparcil is a β-D-thioxyloside derivative and driver of circulating glycosaminoglycan (GAG) synthesis.1,2 It increases the secretion of total sulfated GAGs in bovine aortic endothelial (BAE) cells when used at a concentration of 10 µM.1 Odiparcil (10 µM) reduces intracellular chondroitin sulfate levels in primary skin fibroblasts isolated from patients with mucopolysaccharidosis type VI (MPS VI), an inborn error of metabolism characterized by a deficiency in the degradation of specific GAGs. Dietary administration of odiparcil (4.5 g/kg of chow) increases urinary excretion of sulfated GAGs and decreases hepatic and renal accumulation of sulfated GAGs in a mouse model of MPS VI induced by a homozygous gene mutation in the Arsb gene, which encodes the enzyme arylsulfatase B. Odiparcil reduces thrombus weight in a rat model of thrombosis (ED50 = 3.2 mg/kg).2
WARNING This product is not for human or veterinary use.
Technical Information
| Formal Name | 4-methyl-7- |
| CAS Number | 137215-12-4 |
| Synonyms |
|
| Molecular Formula | C15H16O6S |
| Formula Weight | 324.3 |
| Purity | ≥95% |
| Formulation(Request formulation change) | A solid |
| Solubility(Learn about Variance in Solubility) | Acetonitrile:Water (1:1): Slightly soluble: 0.1-1 mg/mLDMSO: Slightly soluble: 0.1-1 mg/mL |
| SMILES | O=C(OC1=C2)C=C(C)C1=CC=C2O[C@@H]3SC[C@H]([C@@H]([C@H]3O)O)O |
| InChi Code | InChI=1S/C15H16O6S/c1-7-4-12(17)21-11-5-8(2-3-9(7)11)20-15-14(19)13(18)10(16)6-22-15/h2-5,10,13-16,18-19H,6H2,1H3/t10-,13+,14-,15-/m1/s1 |
| InChi Key | JRHNIQQUVJOPQC-AQNFWKISSA-N |
Shipping & Storage Information
| Storage | -20°C |
| Shipping | Room temperature in continental US; may vary elsewhere |
| Stability | ≥ 4 years |
| SKU | CAYM-44255-1 |
|---|---|
| Supplier Part Number | 44255-1 |
| UM | EA |
| UNSPSC | 12352100 |
| Manufacturer | Cayman |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 137215-12-4 |
| Energy Star | No |
| Green | No |
| Controlled | N |