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Cayman Podocarpic Acid, 100 mg


Product Description
Podocarpic acid is a diterpenoid that has been found in D. cupressinum resins and has diverse biological activities.1,2,3 It increases ionic currents in a patch-clamp assay using CHO-K1 cells expressing human large-conductance calcium-activated potassium channels (KCa1.1/BKα) when used at a concentration of 30 µM.1 Podocarpic acid (20 µM) reduces hyperesthesia, neuronal damage, and increases lifespan in a model of α-dicarbonyl-related stress using C. elegans expressing a mutant form of the gene encoding glyoxylase 1.2 It inhibits the infection of MDCK cells by influenza A virus (EC50 = 18.2 µM).3 Podocarpic acid has also been used as a building block in the synthesis of podocarpic acid dimers, such as acetyl podocarpic acid anhydride (APD; Item No. 10007686), with liver X receptor (LXR) agonist activity.4
WARNING This product is not for human or veterinary use.
Technical Information
| Formal Name | 1S,2,3,4,4aS, |
| CAS Number | 5947-49-9 |
| Synonyms |
|
| Molecular Formula | C17H22O3 |
| Formula Weight | 274.4 |
| Purity | ≥98% |
| Formulation(Request formulation change) | A solid |
| Solubility(Learn about Variance in Solubility) | DMSO: Sparingly soluble: 1-10 mg/mLEthanol: Slightly soluble: 0.1-1 mg/mL |
| SMILES | C[C@@]12[C@](CCC3=CC=C(O)C=C32)([H])[C@](C)(CCC1)C(O)=O |
| InChi Code | InChI=1S/C17H22O3/c1-16-8-3-9-17(2,15(19)20)14(16)7-5-11-4-6-12(18)10-13(11)16/h4,6,10,14,18H,3,5,7-9H2,1-2H3,(H,19,20)/t14-,16-,17+/m1/s1 |
| InChi Key | VJILEYKNALCDDV-OIISXLGYSA-N |
| Origin | Synthetic |
Shipping & Storage Information
| Storage | -20°C |
| Shipping | Room temperature in continental US; may vary elsewhere |
| Stability | ≥ 4 years |
| SKU | CAYM-44334-100 |
|---|---|
| Supplier Part Number | 44334-100 |
| UM | EA |
| UNSPSC | 41116113 |
| Manufacturer | Cayman |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | China |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 5947-49-9 |
| Energy Star | No |
| Green | No |
| Controlled | N |

