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Cayman (R,S)-N-Nitrosoanabasine, 10 mg
List Price $302.00 Your Price $302.00
Cayman (R,S)-N-Nitrosoanabasine, 10 mg-CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-44338-10
MFG.PART: 44338-10
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
(R,S)-N-Nitrosoanabasine (NAB) is a tobacco-specific N-nitrosamine (TSNA) that has been found in tobacco products and electronic cigarettes.1,2 It inhibits the metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK; Item No. 16414) into 4-oxo-4-(3-pyridyl) butanal (OPB), 4-hydroxy-1-(3-pyridyl)-1-butanone (HPB), and 4-oxo-4-(3-pyridyl) butanoic acid (OPBA) by the cytochrome P450 (CYP) isoform CYP2A13 with Ki values of 0.23, 0.87, and 0.5 µM, respectively.3 NAB is not carcinogenic in hamsters but is carcinogenic in mice.4,5
WARNING This product is not for human or veterinary use.
Technical Information
| Formal Name | 3-(1-nitroso-2-piperidinyl)-pyridine |
| CAS Number | 37620-20-5 |
| Synonyms |
|
| Molecular Formula | C10H13N3O |
| Formula Weight | 191.2 |
| Purity | ≥98% |
| Formulation(Request formulation change) | A low-melting solid |
| Solubility(Learn about Variance in Solubility) | DMSO: Soluble: ≥ 10 mg/mLEthanol: Soluble: ≥ 10 mg/mLPBS (pH 7.2): Sparingly soluble: 1-10 mg/mL |
| SMILES | O=NN1CCCCC1C2=CC=CN=C2 |
| InChi Code | InChI=1S/C10H13N3O/c14-12-13-7-2-1-5-10(13)9-4-3-6-11-8-9/h3-4,6,8,10H,1-2,5,7H2 |
| InChi Key | BXYPVKMROLGXJI-UHFFFAOYSA-N |
Shipping & Storage Information
| Storage | -20°C |
| Shipping | Room temperature in continental US; may vary elsewhere |
| Stability | ≥ 4 years |
| SKU | CAYM-44338-10 |
|---|---|
| Supplier Part Number | 44338-10 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | China |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | Y |
| CAS Number | 37620-20-5 |
| Energy Star | No |
| Green | No |
| Controlled | N |