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Cayman PRAME (425-433) (human) (trifluoroacetate salt), 10 mg
List Price $93.00 Your Price $93.00
Cayman PRAME (425-433) (human) (trifluoroacetate salt), 10 mg-CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-44403-10
MFG.PART: 44403-10
UNSPSC: 12352202
Manufacturer: Cayman
Product Description
Preferentially expressed antigen in melanoma (PRAME) (425-433) is an immunogenic T cell epitope.1 It binds to HLA-A*0201-positive JY B lymphoblastoid cells with an IC50 value of 3.7 µM. Co-culture of PRAME (425-433)-primed isolated human HLA-A*0201-positive antigen-presenting cells with naïve autologous CD8+ T cells to generate PRAME (425-433)-specific cytotoxic T lymphocytes induces lysis of MCF-7 breast cancer cells.
WARNING This product is not for human or veterinary use.
Technical Information
| Formal Name | (S)-2-((2S,5S, |
| Synonyms |
|
| Molecular Formula | C46H80N12O12 • XCF3COOH |
| Formula Weight | 993.2 |
| Purity | ≥95% |
| Formulation(Request formulation change) | A solid |
| Peptide Sequence | SLLQHLIGL-OH |
| Solubility(Learn about Variance in Solubility) | DMSO: Soluble: ≥ 10 mg/mLEthanol: Sparingly soluble: 1-10 mg/mL |
| SMILES | O=C(N[C@H](C(N[C@H](C(N[C@@H](CCC(N[H])=O)C(N[C@@H](CC1=CN([H])C=N1)C(N[C@H](C(N[C@@](C(NCC(N[C@H](C(O)=O)CC(C)C)=O)=O)([H])[C@@H](C)CC)=O)CC(C)C)=O)=O)=O)CC(C)C)=O)CC(C)C)[C@H](CO[H])N[H].O=C(O)C(F)(F)F |
| InChi Code | InChI=1S/C46H80N12O12.C2HF3O2/c1-11-27(10)38(45(68)50-20-37(61)52-35(46(69)70)17-26(8)9)58-44(67)33(16-25(6)7)56-43(66)34(18-28-19-49-22-51-28)57-40(63)30(12-13-36(48)60)53-41(64)32(15-24(4)5)55-42(65)31(14-23(2)3)54-39(62)29(47)21-59;3-2(4,5)1(6)7/h19,22-27,29-35,38,59H,11-18,20-21,47H2,1-10H3,(H2,48,60)(H,49,51)(H,50,68)(H,52,61)(H,53,64)(H,54,62)(H,55,65)(H,56,66)(H,57,63)(H,58,67)(H,69,70);(H,6,7)/t27-,29-,30-,31-,32-,33-,34-,35-,38-;/m0./s1 |
| InChi Key | LQWXGBQTKWSNSO-VCGXSGBKSA-N |
Shipping & Storage Information
| Storage | -20°C |
| Shipping | Room temperature in continental US; may vary elsewhere |
| Stability | ≥ 4 years |
| SKU | CAYM-44403-10 |
|---|---|
| Supplier Part Number | 44403-10 |
| UM | EA |
| UNSPSC | 12352202 |
| Manufacturer | Cayman |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | China |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| Energy Star | No |
| Green | No |
| Controlled | N |