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Cayman sPLA2 (Type IIA) Inhibitor Screening Assay Kit, 384 Well


Product Description
Cayman’s sPLA2 (Type IIA) Inhibitor Screening Assay Kit provides a robust and easy-to-use platform for identifying novel inhibitors of human sPLA2 type IIA, a phospholipase that preferentially hydrolyzes PG and PE. The assay uses diheptanoyl thio-PE, a sulfur-containing analog of PE as a substrate. Upon hydrolysis by sPLA2 type IIA at the sn-2 position, the free thiol can be detected by the sPLA2 Assay Probe. This results in a product that can be easily quantified by measuring absorbance at a wavelength of 410 nm. A potent and reversible inhibitor, LY315920 (included in this kit as sPLA2 Control Inhibitor), inhibits the enzyme with an average IC50 value of approximately 22 nM.
Needed but not supplied: Please download the kit booklet to verify if UltraPure Water (Milli-Q or equivalent) or any other components are needed for this assay.
WARNING This product is not for human or veterinary use.
Technical Information
| Synonyms |
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Shipping & Storage Information
| Storage | -80°C |
| Shipping | Dry ice in continental US; may vary elsewhere |
| Stability | ≥ 1 year |
| SKU | CAYM-702470-384WELL |
|---|---|
| Supplier Part Number | 702470-384WELL |
| UM | EA |
| UNSPSC | 41116133 |
| Manufacturer | Cayman |
| Temperature | -80 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | Y |
| Energy Star | No |
| Green | No |
| Controlled | N |

