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Sigma-Aldrich Veliparib
List Price
$91.64
Your Price
$91.64
Sigma-Aldrich Veliparib - SIAL (Additional S&H or Hazmat Fees May Apply)
NETA PART:
SIAL-SML4243-5MG
MFG.PART:
SML4243-5MG
UNSPSC:
12352200
Manufacturer:
Sigma-Aldrich
Quality Level
100
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 2 mg/mL, clear (warmed)
storage temp.
-10 to -25°C
Biochem/physiol Actions
Orally active, potent and selective PARP (poly(ADP-ribose) polymerase) inhibitor (Ki = 5.2 nM PARP1, and 2.9 nM PARP2) that exhibits potent anti-cancer activity.
Veliparib (ABT-888) is an orally active, potent and selective PARP (poly(ADP-ribose) polymerase) inhibitor (Ki = 5.2 nM PARP1, and 2.9 nM PARP2) that exhibits potent anti-cancer activity. Veliparib blocks DNA damage repair in cancer cells, additionally rendering them more susceptible for other anti-cancer drugs. As a potent PARP1 and PARP2 inhibitor it induces synthetic lethality in cancer cells.
Veliparib (ABT-888) is an orally active, potent and selective PARP (poly(ADP-ribose) polymerase) inhibitor (Ki = 5.2 nM PARP1, and 2.9 nM PARP2) that exhibits potent anti-cancer activity. Veliparib blocks DNA damage repair in cancer cells, additionally rendering them more susceptible for other anti-cancer drugs. As a potent PARP1 and PARP2 inhibitor it induces synthetic lethality in cancer cells.
| SKU | SIAL-SML4243-5MG |
|---|---|
| Supplier Part Number | SML4243-5MG |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Sigma-Aldrich |
| ProductLine | SIAL |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 9 |
| CAS Number | 912444-00-9 |
| Energy Star | No |
| Green | No |
| Controlled | N |