Sigma-Aldrich Tssk2 Active 10Ug

44.8kDa

FUNCTION: SwissProt: Q96PF2 # Involved in the late stages of spermatogenesis, during the reconstruction of the cytoplasm (By similarity).
COFACTOR: Magnesium (By similarity).
SIZE: 358 amino acids; 40939 Da
SUBUNIT: Binds to STK22A (By similarity).
SUBCELLULAR LOCATION: Cytoplasm (By similarity).
TISSUE SPECIFICITY: Testis.
PTM: Autophosphorylated (By similarity).
DISEASE: SwissProt: Q96PF2 # May play a part in the etiology of the velocardiofacial/DiGeorge syndrome (VCFS/DGS), a developmental disorder characterized by structural and functional palate anomalies, conotruncal cardiac malformations, immunodeficiency, hypocalcemia, and typical facial anomalies. Most cases result from a deletion of chromosome 22q11.2 (the DiGeorge syndrome chromosome region, or DGCR).
SIMILARITY: SwissProt: Q96PF2 ## Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. & Contains 1 protein kinase domain.

Also available in 10 μg size (cat#14-632) and in bulk (cat#14-632-K).

6 months at -70°C

For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.

Routinely evaluated by phosphorylation of CHKtide

routinely evaluated by phosphorylation of CHKtide

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