We use cookies to make your experience better. To comply with the new e-Privacy directive, we need to ask for your consent to set the cookies. Learn about our cookie policy.
Sigma-Aldrich Yaddle1
List Price $555.64 Your Price $555.64
Sigma-Aldrich Yaddle1 - SIAL (Additional S&H or Hazmat Fees May Apply)
NETA PART: SIAL-SML4204-25MG
MFG.PART: SML4204-25MG
UNSPSC: 41122409
Manufacturer: Sigma-Aldrich
Quality Level
100
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 2 mg/mL, clear
storage temp.
2-8°C
General description
Mechanosensitive ion channel Piezo1 agonist with higher potency and greatly improved aqueous solubility than Yoda1.
Yaddle1 is a mechanosensitive ion channel Piezo1 agonist with higher potency (Ca2+ influx EC50/Emax = 0.40 μM/2.6-fold using Piezo1 mCherry-expressing HEK293A) and greatly improved aqueous solubility (26.7 μM at pH 7.4) than Yoda1 (EC50/Emax = 0.50 μM/2.4-fold; solubility = 1.2 μM at pH 7.4).
Yaddle1 is a mechanosensitive ion channel Piezo1 agonist with higher potency (Ca2+ influx EC50/Emax = 0.40 μM/2.6-fold using Piezo1 mCherry-expressing HEK293A) and greatly improved aqueous solubility (26.7 μM at pH 7.4) than Yoda1 (EC50/Emax = 0.50 μM/2.4-fold; solubility = 1.2 μM at pH 7.4).
| SKU | SIAL-SML4204-25MG |
|---|---|
| Supplier Part Number | SML4204-25MG |
| UM | EA |
| UNSPSC | 41122409 |
| Manufacturer | Sigma-Aldrich |
| ProductLine | SIAL |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 9 |
| CAS Number | 3041134-13-5 |
| Energy Star | No |
| Green | No |
| Controlled | N |