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Sigma-Aldrich Ofloxacin Hydrochloride
List Price $207.64 Your Price $207.64
Sigma-Aldrich Ofloxacin Hydrochloride - SIAL (Additional S&H or Hazmat Fees May Apply)
NETA PART: SIAL-SML4221-1000MG
MFG.PART: SML4221-1000MG
UNSPSC: 51102800
Manufacturer: Sigma-Aldrich
Quality Level
100
assay
≥98% (HPLC)
form
powder
storage condition
desiccated
color
white to beige
solubility
H2O: 2 mg/mL, clear
storage temp.
-10 to -25°C
SMILES string
O=C(O)C1=CN2C3=C(OCC2C)C(N4CCN(C)CC4)=C(F)C=C3C1=O.[xHCl]
Biochem/physiol Actions
Broad-spectrum fluoroquinolone antibiotic, exhibits water solubility.
Ofloxacin is a fluoroquinolone antibiotic with broad-spectrum activity, which kills bacteria by blocking DNA gyrase and type IV topoisomerase—critical enzymes for DNA replication and transcription—leading to cell death. Ofloxacin has 100 times higher affinity for bacterial DNA gyrase than for mammalian. It is effective against a broad array of both Gram-positive and Gram-negative bacteria, in addition to Mycoplasmas. While the hydrochloride form of ofloxacin is soluble in water, ofloxacin itself is only sparingly soluble in aqueous solutions.
Ofloxacin is a fluoroquinolone antibiotic with broad-spectrum activity, which kills bacteria by blocking DNA gyrase and type IV topoisomerase—critical enzymes for DNA replication and transcription—leading to cell death. Ofloxacin has 100 times higher affinity for bacterial DNA gyrase than for mammalian. It is effective against a broad array of both Gram-positive and Gram-negative bacteria, in addition to Mycoplasmas. While the hydrochloride form of ofloxacin is soluble in water, ofloxacin itself is only sparingly soluble in aqueous solutions.
Disclaimer
Hygroscopic Store with dessicant
| SKU | SIAL-SML4221-1000MG |
|---|---|
| Supplier Part Number | SML4221-1000MG |
| UM | EA |
| UNSPSC | 51102800 |
| Manufacturer | Sigma-Aldrich |
| ProductLine | SIAL |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 9 |
| CAS Number | 118120-51-7 |
| Energy Star | No |
| Green | No |
| Controlled | N |