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Sigma-Aldrich Kd-Validated Anti Transmembrane Protein&
List Price $558.88 Your Price $558.88
Sigma-Aldrich Kd-Validated Anti Transmembrane Protein& - SIAL (Additional S&H or Hazmat Fees May Apply)
NETA PART: SIAL-SAB6012453-100UL
MFG.PART: SAB6012453-100UL
UNSPSC: 41116126
Manufacturer: Sigma-Aldrich
biological source
rabbit (Monoclonal)
Quality Level
100
recombinant
expressed in HEK 293 cells
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
24GB2325, recombinant monoclonal
form
buffered aqueous glycerol solution
mol wt
45 kDa
species reactivity
rat, human
packaging
vial of 1.5 mL
enhanced validation
recombinant expression
Learn more about Antibody Enhanced Validation
concentration
1.5 mg/mL
technique(s)
flow cytometry: 1:2000
western blot: 1:1,000-1:5,000
isotype
IgG
Ensembl | human accession no.
ENSG00000170876
NCBI accession no.
NP_077310.1
UniProt accession no.
Q9BTV4
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... TMEM43(79188)
General description
This gene belongs to the TMEM43 family. Defects in this gene are the cause of familial arrhythmogenic right ventricular dysplasia type 5 (ARVD5), also known as arrhythmogenic right ventricular cardiomyopathy type 5 (ARVC5). Arrhythmogenic right ventricular dysplasia is an inherited disorder, often involving both ventricles, and is characterized by ventricular tachycardia, heart failure, sudden cardiac death, and fibrofatty replacement of cardiomyocytes. This gene contains a response element for PPAR gamma (an adipogenic transcription factor), which may explain the fibrofatty replacement of the myocardium, a characteristic pathological finding in ARVC. [provided by RefSeq, Oct 2008]
Immunogen
A synthesized peptide corresponding to a sequence within amino acids 100-135 of human TMEM43 [NP_077310.1].
Physical form
Solution in PBS (pH 7.4) containing 50% glycerol, and 0.02% sodium azide.
Other Notes
Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.
| SKU | SIAL-SAB6012453-100UL |
|---|---|
| Supplier Part Number | SAB6012453-100UL |
| UM | EA |
| UNSPSC | 41116126 |
| Manufacturer | Sigma-Aldrich |
| ProductLine | SIAL |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 9 |
| Energy Star | No |
| Green | No |
| Controlled | N |