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Sigma-Aldrich Kd-Validated Anti Picalm Antibody Clon&
List Price $558.88 Your Price $558.88
Sigma-Aldrich Kd-Validated Anti Picalm Antibody Clon& - SIAL (Additional S&H or Hazmat Fees May Apply)
NETA PART: SIAL-SAB6012532-100UL
MFG.PART: SAB6012532-100UL
UNSPSC: 41116161
Manufacturer: Sigma-Aldrich
biological source
rabbit (Monoclonal)
Quality Level
100
recombinant
expressed in HEK 293 cells
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
24GB1620, recombinant monoclonal
form
buffered aqueous glycerol solution
mol wt
71 kDa
species reactivity
human
packaging
vial of 1.5 mL
enhanced validation
recombinant expression
Learn more about Antibody Enhanced Validation
concentration
0.7 mg/mL
technique(s)
flow cytometry: 1:2000
western blot: 1:1,000-1:5,000
isotype
IgG
Ensembl | human accession no.
ENSG00000073921
NCBI accession no.
NP_009097.2
UniProt accession no.
Q13492
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... PICALM(8301)
General description
This gene encodes a clathrin assembly protein, which recruits clathrin and adaptor protein complex 2 (AP2) to cell membranes at sites of coated-pit formation and clathrin-vesicle assembly. The protein may be required to determine the amount of membrane to be recycled, possibly by regulating the size of the clathrin cage. The protein is involved in AP2-dependent clathrin-mediated endocytosis at the neuromuscular junction. A chromosomal translocation t(10;11)(p13;q14) leading to the fusion of this gene and the MLLT10 gene is found in acute lymphoblastic leukemia, acute myeloid leukemia and malignant lymphomas. The polymorphisms of this gene are associated with the risk of Alzheimer disease. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2011]
Immunogen
A synthesized peptide corresponding to a sequence within amino acids 550-600 of human PICALM [NP_009097.2].
Physical form
Solution in PBS (pH 7.4) containing 50% glycerol, and 0.02% sodium azide.
Other Notes
Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.
| SKU | SIAL-SAB6012532-100UL |
|---|---|
| Supplier Part Number | SAB6012532-100UL |
| UM | EA |
| UNSPSC | 41116161 |
| Manufacturer | Sigma-Aldrich |
| ProductLine | SIAL |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 9 |
| Energy Star | No |
| Green | No |
| Controlled | N |