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Sigma-Aldrich Kd-Validated Anti Mcm3 Antibody Clone &
List Price $523.95 Your Price $523.95
Sigma-Aldrich Kd-Validated Anti Mcm3 Antibody Clone & - SIAL (Additional S&H or Hazmat Fees May Apply)
NETA PART: SIAL-SAB6012314-100UL
MFG.PART: SAB6012314-100UL
UNSPSC: 41116161
Manufacturer: Sigma-Aldrich
biological source
rabbit (Monoclonal)
Quality Level
100
recombinant
expressed in HEK 293 cells
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
23GB2490, recombinant monoclonal
form
buffered aqueous glycerol solution
mol wt
91 kDa
species reactivity
rat, human
packaging
vial of 1.5 mL
enhanced validation
recombinant expression
Learn more about Antibody Enhanced Validation
concentration
0.4 mg/mL
technique(s)
immunofluorescence: 1:100-:1000
western blot: 1:1,000-1:5,000
isotype
IgG
Ensembl | human accession no.
ENSG00000112118
NCBI accession no.
NP_001257401.1
UniProt accession no.
P25205
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... MCM3(4172)
General description
The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein is a subunit of the protein complex that consists of MCM2-7. It has been shown to interact directly with MCM5/CDC46. This protein also interacts with and is acetylated by MCM3AP, a chromatin-associated acetyltransferase. The acetylation of this protein inhibits the initiation of DNA replication and cell cycle progression. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2018]
Immunogen
A synthesized peptide corresponding to a sequence within amino acids 1-44 of human MCM3 [NP_001257401.1].
Physical form
Solution in PBS (pH 7.4) containing 50% glycerol, and 0.02% sodium azide.
Other Notes
Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.
| SKU | SIAL-SAB6012314-100UL |
|---|---|
| Supplier Part Number | SAB6012314-100UL |
| UM | EA |
| UNSPSC | 41116161 |
| Manufacturer | Sigma-Aldrich |
| ProductLine | SIAL |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 9 |
| Energy Star | No |
| Green | No |
| Controlled | N |