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Sigma-Aldrich Kd-Validated Anti Cytoplasmic Fmr1 Inte&
List Price
$523.95
Your Price
$523.95
Sigma-Aldrich Kd-Validated Anti Cytoplasmic Fmr1 Inte& - SIAL (Additional S&H or Hazmat Fees May Apply)
NETA PART:
SIAL-SAB6012364-100UL
MFG.PART:
SAB6012364-100UL
UNSPSC:
41116010
Manufacturer:
Sigma-Aldrich
biological source
rabbit (Monoclonal)
Quality Level
100
recombinant
expressed in HEK 293 cells
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
23GB1605, recombinant monoclonal
form
buffered aqueous glycerol solution
mol wt
145 kDa
species reactivity
rat, human
packaging
vial of 1.5 mL
enhanced validation
recombinant expression
Learn more about Antibody Enhanced Validation
concentration
0.5 mg/mL
technique(s)
flow cytometry: 1:2000
immunofluorescence: 1:100-:1000
western blot: 1:1,000-1:5,000
isotype
IgG
Ensembl | human accession no.
ENSG00000273749
NCBI accession no.
NP_055423.1
UniProt accession no.
Q7L576
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... CYFIP1(23191)
General description
This gene encodes a protein that regulates cytoskeletal dynamics and protein translation. The encoded protein is a component of the WAVE regulatory complex (WRC), which promotes actin polymerization. This protein also interacts with the synaptic functional regulator FMR1 protein and translation initiation factor 4E to inhibit protein translation. A large chromosomal deletion including this gene is associated with increased risk of schizophrenia and epilepsy in human patients. Reduced expression of this gene has been observed in various human cancers and the encoded protein may inhibit tumor invasion. [provided by RefSeq, Mar 2022]
Immunogen
A synthesized peptide corresponding to a sequence within amino acids 50-100 of human CYFIP1 [NP_055423.1].
Physical form
Solution in PBS (pH 7.4) containing 50% glycerol, and 0.02% sodium azide.
Other Notes
Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.
| SKU | SIAL-SAB6012364-100UL |
|---|---|
| Supplier Part Number | SAB6012364-100UL |
| UM | EA |
| UNSPSC | 41116010 |
| Manufacturer | Sigma-Aldrich |
| ProductLine | SIAL |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 9 |
| Energy Star | No |
| Green | No |
| Controlled | N |