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Sigma-Aldrich Anti Rb1 Antibody Clone 23Gb2535 Rabb&
List Price $324.45 Your Price $324.45
Sigma-Aldrich Anti Rb1 Antibody Clone 23Gb2535 Rabb& - SIAL (Additional S&H or Hazmat Fees May Apply)
NETA PART: SIAL-SAB6012221-100UL
MFG.PART: SAB6012221-100UL
UNSPSC: 41116010
Manufacturer: Sigma-Aldrich
biological source
rabbit (Monoclonal)
Quality Level
100
recombinant
expressed in HEK 293 cells
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
23GB2535, recombinant monoclonal
form
buffered aqueous glycerol solution
mol wt
106 kDa
species reactivity
human
packaging
vial of 1.5 mL
enhanced validation
recombinant expression
Learn more about Antibody Enhanced Validation
concentration
1.5 mg/mL
technique(s)
flow cytometry: 1:2000
immunofluorescence: 1:100-:1000
western blot: 1:1,000-1:5,000
isotype
IgG
Ensembl | human accession no.
ENSG00000139687
NCBI accession no.
NP_000312.2
UniProt accession no.
P06400
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... RB1(5925)
General description
The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma. [provided by RefSeq, Jul 2008]
Immunogen
A synthesized peptide corresponding to a sequence within amino acids 701-928 of human Retinoblastoma [NP_000312.2].
Physical form
Solution in PBS (pH 7.4) containing 50% glycerol, and 0.02% sodium azide.
Other Notes
Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.
| SKU | SIAL-SAB6012221-100UL |
|---|---|
| Supplier Part Number | SAB6012221-100UL |
| UM | EA |
| UNSPSC | 41116010 |
| Manufacturer | Sigma-Aldrich |
| ProductLine | SIAL |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 9 |
| Energy Star | No |
| Green | No |
| Controlled | N |