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Sigma-Aldrich Acetic Anhydride >=99% Liquid Reagen&
List Price $319.30 Your Price $319.30
Sigma-Aldrich Acetic Anhydride >=99% Liquid Reagen& - SIAL (Additional S&H or Hazmat Fees May Apply)
NETA PART: SIAL-320102-4L
MFG.PART: 320102-4L
UNSPSC: 12350000
Manufacturer: Sigma-Aldrich
Product Name
Acetic anhydride, ReagentPlus®, ≥99%
vapor density
3.5 (vs air)
Quality Level
200
vapor pressure
10 mmHg ( 36 °C)
4 mmHg ( 20 °C)
product line
ReagentPlus®
assay
≥99%
form
liquid
autoignition temp.
629 °F
expl. lim.
10.3 %
refractive index
n20/D 1.390 (lit.)
bp
138-140 °C (lit.)
mp
−73 °C (lit.)
solubility
water: slightly soluble
density
1.08 g/mL (lit.)
functional group
anhydride
ester
SMILES string
CC(=O)OC(C)=O
InChI
1S/C4H6O3/c1-3(5)7-4(2)6/h1-2H3
InChI key
WFDIJRYMOXRFFG-UHFFFAOYSA-N
General description
Acetic anhydride is a carboxylic acid anhydride commonly used as an acetylating agent for amines and alcohols.[1]
Acetic anhydride participates in the Friedel-Craft′s intramolecular cyclization reaction of cyclopropyl ketones to afford the tetralones.[2] It has been reported to promote the Knoevenagel condensation of various aldehydes and activated methylene compounds.[3]
Application
Acetic anhydride may be used as a reactant to synthesize:
- 3-acetoxybenzoic acid by reacting with 3-hydroxybenzoic acid[4]
- 6-dimethylamino-2,3-naphthalenedicarboxylic anhydride, a precursor to prepare 6-dimethylaminonaphthalimide[5]
Acetic anhydride was used in the following studies:
- Lipozyme TL IM (commercial immobilized lipase from Thermomyces lanuginosus) catalyzed acetylation of essential clove oil.[6]
- As acetyl donor to investigate the lipase catalyzed acetylation of nanofibrillated cellulose (NFC).[7]
- Synthesis of N-substituted pyrazolines.[8]
- Acetylation of Barnyardgrass (Echinochloa crus-galli) starch.[9]
Legal Information
ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany
pictograms
GHS02,GHS06,GHS05
signalword
Danger
hcodes
H226,H302,H314,H330
pcodes
P210 - P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
Hazard Classifications
Acute Tox. 2 Inhalation - Acute Tox. 4 Oral - Eye Dam. 1 - Flam. Liq. 3 - Skin Corr. 1B
Storage Class
3 - Flammable liquids
wgk_germany
WGK 1
flash_point_f
120.2 °F - closed cup
flash_point_c
49 °C - closed cup
PPE
Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
| SKU | SIAL-320102-4L |
|---|---|
| Supplier Part Number | 320102-4L |
| UM | EA |
| UNSPSC | 12350000 |
| Manufacturer | Sigma-Aldrich |
| ProductLine | SIAL |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 9 |
| CAS Number | 108-24-7 |
| Energy Star | No |
| Green | No |
| Controlled | N |