We use cookies to make your experience better. To comply with the new e-Privacy directive, we need to ask for your consent to set the cookies. Learn about our cookie policy.
Sigma-Aldrich Prame (Ep461) 25Ml Predilute
List Price
$1,637.50
Your Price
$1,637.50
Sigma-Aldrich Prame (Ep461) 25Ml Predilute - SIAL (Additional S&H or Hazmat Fees May Apply)
NETA PART:
SIAL-484R-10
MFG.PART:
484R-10
UNSPSC:
41116161
Manufacturer:
Sigma-Aldrich
biological source
rabbit
Quality Level
100
500
conjugate
unconjugated
antibody form
culture supernatant
antibody product type
primary antibodies
clone
EP461, monoclonal
description
For In Vitro Diagnostic Use in Select Regions
form
buffered aqueous solution
species reactivity
human
packaging
vial of 0.1 mL concentrate (484R-14)
vial of 0.1 mL concentrate Research Use Only (484R-14-RUO)
vial of 0.5 mL concentrate (484R-15)
vial of 1.0 mL concentrate (484R-16)
vial of 1.0 mL concentrate Research Use Only (484R-16-RUO)
vial of 1.0 mL pre-dilute Research Use Only (484R-17-RUO)
vial of 1.0 mL pre-dilute ready-to-use (484R-17)
vial of 25.0 mL pre-dilute ready-to-use Research Use Only (484R-10-RUO)
vial of 25.0 mL pre-dilute ready-to-use (484R-10)
vial of 7.0 mL pre-dilute ready-to-use (484R-18)
vial of 7.0 mL pre-dilute ready-to-use Research Use Only (484R-18-RUO)
technique(s)
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25-1:50 (concentrated)
isotype
IgG
control
melanoma
shipped in
wet ice
storage temp.
2-8°C
visualization
nuclear
General description
PRAME (PReferentially-expressed Antigen in MElanoma) is a gene encoded on the 22q11-22 chromosomal sequence and encodes a 509 amino acid residue protein.1 PRAME is a melanoma antigen that is preferentially expressed in tumors and is recognized by cytotoxic T lymphocytes.2,3 PRAME can be used to distinguish between malignant melanoma cells and nevus cells,4 and therefore may be useful for diagnostic purposes to support a suspected case of melanoma. PRAME is considered a cancer-testis antigen (CTA)5 and is not strongly expressed in most other normal tissues. PRAME is positively expressed in about half of uveal melanomas,6 and the majority of mucosal melanomas.7
Physical form
Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and < 0.1% Sodium Azide.
Preparation Note
Download the IFU specific to your product lot and format
Note: This requires a keycode which can be found on your packaging or product label.
Note: This requires a keycode which can be found on your packaging or product label.
Analysis Note
- United States - IVD
- Canada - RUO
- European Union - IVD
- Japan - RUO
Other Notes
For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com
Storage Class
12 - Non Combustible Liquids
wgk_germany
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
| SKU | SIAL-484R-10 |
|---|---|
| Supplier Part Number | 484R-10 |
| UM | EA |
| UNSPSC | 41116161 |
| Manufacturer | Sigma-Aldrich |
| ProductLine | SIAL |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 9 |
| Energy Star | No |
| Green | No |
| Controlled | N |