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Sigma-Aldrich Ghrelin(Active)Ria125Tkit I-125<55.5Kbqs
List Price
$870.00
Your Price
$870.00
Sigma-Aldrich Ghrelin(Active)Ria125Tkit I-125
NETA PART:
SIAL-GHRA-88HK
MFG.PART:
GHRA-88HK
UNSPSC:
12142207
Manufacturer:
Sigma-Aldrich
description
ED<sub>80</sub> = 27 ± 7pg/mL ED<sub>50</sub>=125 ± 33 pg/mL ED<sub>20</sub>=652 ± 179 pg/mL
analytes available: Ghrelin
for protein analysis
10-2000 pg/mL (standard curve range)
Quality Level
100
feature
accuracy 83–114%
species reactivity
human
sensitivity measuring range
10 pg/mL
technique(s)
radioimmunoassay: suitable
UniProt accession no.
Q9UBU3
detection method
radioactive
General description
FUNCTION: SwissProt: Q9UBU3 # Obestatin may be the ligand for GPR39. May have an appetite-reducing effect resulting in decreased food intake. May reduce gastric emptying activity and jejunal motility (By similarity).
SIZE: 117 amino acids; 12911 Da
SUBCELLULAR LOCATION: Secreted.
TISSUE SPECIFICITY: Highest level in stomach. All forms are found in serum as well. Other tissues compensate for the loss of ghrelin synthesis in the stomach following gastrectomy.
PTM: O-octanoylation or O-decanoylation is essential for ghrelin activity. The O-decanoylated forms Ghrelin-27-C10 and Ghrelin-28- C10 differ in the length of the carbon backbone of the carboxylic acid bound to Ser-26. A small fraction of ghrelin, ghrelin-28- C10:1, may be modified with a singly unsaturated carboxylic acid. & Amidation of Leu-98 is essential for obestatin activity (By similarity).
SIMILARITY: SwissProt: Q9UBU3 ## Belongs to the motilin family.
SIZE: 117 amino acids; 12911 Da
SUBCELLULAR LOCATION: Secreted.
TISSUE SPECIFICITY: Highest level in stomach. All forms are found in serum as well. Other tissues compensate for the loss of ghrelin synthesis in the stomach following gastrectomy.
PTM: O-octanoylation or O-decanoylation is essential for ghrelin activity. The O-decanoylated forms Ghrelin-27-C10 and Ghrelin-28- C10 differ in the length of the carbon backbone of the carboxylic acid bound to Ser-26. A small fraction of ghrelin, ghrelin-28- C10:1, may be modified with a singly unsaturated carboxylic acid. & Amidation of Leu-98 is essential for obestatin activity (By similarity).
SIMILARITY: SwissProt: Q9UBU3 ## Belongs to the motilin family.
Application
Two-day disequilibrium assay at 4°C. Sample volume: ≤ 100 μL Plasma (collected on ice) recommended
Analysis Note
Linearity 100–142.5%
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
pictograms
GHS02,GHS06,GHS08,GHS09
signalword
Danger
hcodes
H226,H302 + H332,H311,H370,H373,H411
pcodes
P210 - P273 - P280 - P303 + P361 + P353 - P304 + P340 + P312 - P308 + P311
Hazard Classifications
Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Flam. Liq. 3 - STOT RE 2 Inhalation - STOT SE 1
target_organs
Eyes,Central nervous system, Respiratory Tract
Storage Class
3 - Flammable liquids
| SKU | SIAL-GHRA-88HK |
|---|---|
| Supplier Part Number | GHRA-88HK |
| UM | EA |
| UNSPSC | 12142207 |
| Manufacturer | Sigma-Aldrich |
| ProductLine | SIAL |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 9 |
| Energy Star | No |
| Green | No |
| Controlled | N |