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Sigma-Aldrich Human Leptin Ria 250 Tkit I-125<55.5Kbqs
List Price $685.00 Your Price $685.00
Sigma-Aldrich Human Leptin Ria 250 Tkit I-125
NETA PART: SIAL-HL-81HK
MFG.PART: HL-81HK
UNSPSC: 12142207
Manufacturer: Sigma-Aldrich
description
ED<sub>80</sub> = 0.9 ± 0.1 ng/mL ED<sub>50</sub> = 4.5 ± 0.4 ng/mL ED<sub>20</sub> = 22.2 ± 2.8 ng/mL
ED<sub>80</sub> = 1.2 ± 0.1 ng/mL ED<sub>50</sub> = 5.1 ± 0.4 ng/mL ED<sub>20</sub> = 23.7 ± 2.1 ng/mL
analytes available: Leptin
for protein analysis
0.5-100 ng/mL (standard curve range)
Quality Level
100
feature
accuracy 103–105%
species reactivity
human
technique(s)
radioimmunoassay: suitable
UniProt accession no.
P41159
detection method
radioactive
General description
FUNCTION: SwissProt: P41159 # May function as part of a signaling pathway that acts to regulate the size of the body fat depot. An increase in the level of LEP may act directly or indirectly on the CNS to inhibit food intake and/or regulate energy expenditure as part of a homeostatic mechanism to maintain constancy of the adipose mass.
SIZE: 167 amino acids; 18641 Da
SUBUNIT: Interacts with SIGLEC6.
SUBCELLULAR LOCATION: Secreted.
DISEASE:SwissProt: P41159 # Defects in LEP may be a cause of autosomal recessive obesity [MIM:601665].
SIMILARITY: SwissProt: P41159 ## Belongs to the leptin family.
SIZE: 167 amino acids; 18641 Da
SUBUNIT: Interacts with SIGLEC6.
SUBCELLULAR LOCATION: Secreted.
DISEASE:SwissProt: P41159 # Defects in LEP may be a cause of autosomal recessive obesity [MIM:601665].
SIMILARITY: SwissProt: P41159 ## Belongs to the leptin family.
Application
Overnight, equilibrium incubation at 4°C. Sample volume 100 μL serum, plasma, or tissue culture media.
Analysis Note
Linearity 88–101%
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
| SKU | SIAL-HL-81HK |
|---|---|
| Supplier Part Number | HL-81HK |
| UM | EA |
| UNSPSC | 12142207 |
| Manufacturer | Sigma-Aldrich |
| ProductLine | SIAL |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 9 |
| Energy Star | No |
| Green | No |
| Controlled | N |