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Sigma-Aldrich Quictpd# Crbn Ligand Set
List Price $355.00 Your Price $355.00
Sigma-Aldrich Quictpd# Crbn Ligand Set - SIAL (Additional S&H or Hazmat Fees May Apply)
NETA PART: SIAL-QCRBNSET-1KT
MFG.PART: QCRBNSET-1KT
UNSPSC: 12142207
Manufacturer: Sigma-Aldrich
packaging
pkg of 50 mg
Quality Level
100
sustainability
Greener Alternative Product
greener alternative category
DfS-Developed
storage temp.
2-8°C
Related Categories
Greener Alternative Products
General description
5-Amino Thalidomide, Lenalidomide, Pomalidomide and C-5 Lenalidomide are recruiters of CRBN protein that can be leveraged for targeted protein degradation research. They are provided at 50 mg each.
We are committed to bringing you Greener Alternative Products. This product is a Design for Sustainability (DfS) developed product, which belongs to one of the four categories of greener alternatives. Click here to view its DfS scorecard.
Application
Useful for construction of CRBN based partial protacs of full protacs, by utilizing the amine terminus to add suitable linkers with peptide coupling reactions. These can also be used as controls/competitors to confirm target engagement of putative protacs.
Features and Benefits
Quantities provided are sufficient to do atleast 96 reactions at 2 micromole each with a D2B approach with a library of suitable bifunctional linkers ending in carboxylic acid terminus to generate a library of partial protacs or full protacs.
Other Notes
CRBN Ligand Set part of QuicTPD™ kit
Legal Information
QuicTPD is a trademark of Merck KGaA, Darmstadt, Germany
pictograms
GHS06,GHS08
signalword
Danger
hcodes
H301,H312,H360FD,H373
pcodes
P202 - P260 - P264 - P280 - P301 + P310 - P302 + P352 + P312
Hazard Classifications
Acute Tox. 3 Oral - Acute Tox. 4 Dermal - Repr. 1A - STOT RE 2
target_organs
Blood
Storage Class
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk_germany
WGK 3
| SKU | SIAL-QCRBNSET-1KT |
|---|---|
| Supplier Part Number | QCRBNSET-1KT |
| UM | EA |
| UNSPSC | 12142207 |
| Manufacturer | Sigma-Aldrich |
| ProductLine | SIAL |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 9 |
| Energy Star | No |
| Green | No |
| Controlled | N |