Cayman Prostaglandin D Synthase (lipocalin-type; human) ELISA Kit, 96 wells

Product Description

Prostaglandin D synthase (PGDS) catalyzes the isomerization of PGH₂ to produce PGD₂, a potent lipid mediator involved in sleep regulation, nociception, platelet aggregation, and allergic and inflammatory responses. Lipocalin-type PGDS (a.k.a. β-trace) is a homodimer with each subunit ranging in size from 20-31 kDa, depending on the extent of glycosylation. L-PGDS has two functions: it catalyzes the conversion of PGH₂ to PGD₂ and acts as a carrier protein for lipid-like molecules (i.e., retinoids and thyroid hormones).¹ L-PGDS is present in a variety of body fluids including cerebrospinal fluid, seminal fluid, and plasma. Cayman’s L-PGDS (human) ELISA is an immunometric (i.e., sandwich) ELISA with a standard curve ranging from 1.56-100 ng/mL and a limit of detection of 1.56 ng/mL. Inter- and intra-assay CV’s of less than 15% may be achieved at most concentrations. This assay has been validated using cerebrospinal fluid which contains approximately 12-30 µg/mL of L-PGDS.

Needed but not supplied: Please download the kit booklet to verify if UltraPure Water (Milli-Q or equivalent) or any other components are needed for this assay.

WARNING This product is not for human or veterinary use.

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