Cayman Prostaglandin D2 ELISA Kit, 480 solid wells

Product Description

Prostaglandin D₂ (PGD₂) is biosynthesized in the brain by a soluble, 26 kDa glutathione-independent lipocalin-type PGD₂ synthase. This PGD₂ accumulates in the cerebrospinal fluid (CSF), where it induces physiologic sleep in rats and humans. PGD₂ is also synthesized in mast cells and leukocytes by a cellular, myeloid-type, glutathione-dependent PGD synthase. This PGD₂ which is formed in the intracellular and vascular compartments is rapidly metabolized to 11β-PGF_2α and other metabolites. Measurement of the parent eicosanoid PGD₂ is appropriate in cell culture lysates and in CSF, where concentrations of several hundred pg/mL have been measured. Cayman’s PGD₂ ELISA Kit is a competitive assay that can be used for quantification of PGD₂ in cell culture lysates and enzymatic reactions.

Needed but not supplied: Please download the kit booklet to verify if UltraPure Water (Milli-Q or equivalent) or any other components are needed for this assay.

WARNING This product is not for human or veterinary use.

Technical Information

Shipping & Storage Information