Cayman Latanoprost ELISA Kit, 480 solid wells

Name: Cayman Latanoprost ELISA Kit, 480 solid wells
SKU: CAYM-516811-480SOLID
Price: 1176.00 USD

List Price $1,176.00 Your Price $1,176.00

Cayman Latanoprost ELISA Kit, 480 solid wells-CAYM (Additional S&H Or Hazmat Fees May Apply)

NETA PART: CAYM-516811-480SOLID

MFG.PART: 516811-480SOLID

UNSPSC: 41116158

Manufacturer: Cayman

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Description

Product Description

Latanoprost is 13,14-dihydro-17-phenyl-18,19,20-trinor prostaglandin F_2α isopropyl ester (13,14-dihydro-17-phenyl-18,19,20-trinor PGF_2α isopropyl ester), an F-series prostaglandin analog which has been approved for use as an ocular hypotensive drug.^1,2,3 Prostaglandin esters and other similar derivatives act as prodrugs which are converted to the active free acid form by an esterase/amidase activity in ocular tissues. The free acid form of Latanoprost (Latanoprost free acid (Lat-FA), or PhXA 85) is 200 times more potent than the isopropyl ester as an FP receptor ligand tested using the recombinant human FP receptor.² Although the exact mechanism of the intraocular hypotensive effect of prostaglandins is unknown, it correlates very closely with the FP receptor ligand binding affinity of FP receptor agonists.⁴ The Cayman Latanoprost ELISA is a sensitive detection method for measuring the free acid form of Latanoprost. It also detects the isopropyl ester form of Latanoprost, but with less sensitivity. The assay is most appropriate for use when only one of the two forms is present. Samples containing mixtures of both the isopropyl ester and free acid should be purified and the two compounds separated prior to ELISA analysis.

Needed but not supplied: Please download the kit booklet to verify if UltraPure Water (Milli-Q or equivalent) or any other components are needed for this assay.

WARNING This product is not for human or veterinary use.

Technical Information

Synonyms	Latanoprost EIA Kit 17-phenyl-13,14-dihydro trinor Prostaglandin F_2α 17-phenyl-13,14-dihydro trinor Prostaglandin F_2α isopropyl ester PhXA 85
Assay Range	3.9-500 pg/mL (free acid) and 15.6-2,000 pg/mL (ester)
Sensitivity	80% B/B₀: 15.5 pg/mL (free acid) and 43 pg/mL (ester)
Cross Reactivity	(Latanoprost (free acid)) 100%(5-trans Latanoprost) 25.4%(Latanoprost) 25%(17-phenyl Prostaglandin F_2α) 3%(17-phenyl Prostaglandin F_2α ethyl amide) 0.70%(15-epi Latanoprost) 0.16%(15-keto Latanoprost) 0.10%(Fluprostenol) <0.01%(Fluprostenol isopropyl ester) <0.01%(2,3-dinor Fluprostenol) <0.01%(9-keto Fluprostenol) <0.01%(11-keto Fluprostenol) <0.01%(tetranor-PGEM) <0.01%(tetranor-PGFM) <0.01%(Prostaglandin D₂) <0.01%(Prostaglandin E₂) <0.01%(Prostaglandin E₂ Ethanolamide) <0.01%(6-keto Prostaglandin F_1α) <0.01%(Prostaglandin F_2α) <0.01%(Prostaglandin F_2α Ethanolamide) <0.01%(5-trans Prostaglandin F_2α) <0.01%(Thromboxane B₂) <0.01%(Unoprostone) <0.01%(Unoprostone isopropyl ester) <0.01%
Origin	Animal/Bovine, Animal/Eel, Animal/Mouse, Animal/Rabbit

Shipping & Storage Information

Storage	-20°C
Shipping	Wet ice in continental US; may vary elsewhere
Stability	≥ 2 years

Specifications

More Information
SKU	CAYM-516811-480SOLID
Supplier Part Number	516811-480SOLID
UM	EA
UNSPSC	41116158
Manufacturer	Cayman
Temperature	-20
Refrigerated-Frozen	Y
CountryOfOrigin	United States
ProductLine	CAYM
Qty	1
MinOrderQty	1
Weight	7.000000
Lead Time	5
Hazardous	Y
Energy Star	No
Green	No
Controlled	N

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Cayman Latanoprost ELISA Kit, 480 solid wells

Product Description

Technical Information

Shipping & Storage Information

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