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Cayman Melanocortin-4 Receptor Reporter Assay Kit, 100 tests
List Price $511.00 Your Price $511.00
Cayman Melanocortin-4 Receptor Reporter Assay Kit, 100 tests-CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-600190-1EA
MFG.PART: 600190-1EA
UNSPSC: 41106513
Manufacturer: Cayman
Product Description
The melanocortin-4 receptor (MC4R) has important roles in weight regulation, sexual function, and inflammation. Mice deficient in MC4R have increased lipid deposition associated with elevated adiposity, while mutations in MC4R in humans are associated with early onset or severe obesity. This assay consists of a 96-well plate coated with a transfection complex containing DNA constructs for MC4R and a cAMP response element regulated Secreted Alkaline Phosphatase (SEAP) reporter (MC4R Reverse Transfection Strip Plate). Cells grown on the transfection complex will express MC4R at the cell surface. Binding of agonists to MC4R initiates a signal transduction cascade resulting in expression of SEAP which is secreted into the cell culture media. SEAP activity is measured following addition of a luminescence-based alkaline phosphatase substrate provided in the kit.
WARNING This product is not for human or veterinary use.
Technical Information
| Synonyms |
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Shipping & Storage Information
| Storage | -20°C |
| Shipping | Wet ice in continental US; may vary elsewhere |
| Stability | ≥ 1 year |
| SKU | CAYM-600190-1EA |
|---|---|
| Supplier Part Number | 600190-1EA |
| UM | EA |
| UNSPSC | 41106513 |
| Manufacturer | Cayman |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| Energy Star | No |
| Green | No |
| Controlled | N |