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Cayman GPX4 Inhibitor Screening Assay Kit, 96 wells
List Price $576.00 Your Price $576.00
Cayman GPX4 Inhibitor Screening Assay Kit, 96 wells-CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-701880-96WELL
MFG.PART: 701880-96WELL
UNSPSC: 41116012
Manufacturer: Cayman
Product Description
Caymans GPX4 Inhibitor Screening Assay Kit provides a robust and easy-to-use platform for identifying novel inhibitors of human GPX4, a negative regulator of the ferroptosis pathway. The assay measures GPX4 indirectly by a coupled reaction with glutathione reductase (GR). Oxidized glutathione (GSSG), produced upon reduction of hydroperoxide by GPX4, is recycled to its reduced state by GR and NADPH. The oxidation of NADPH to NADP+ is accompanied by a decrease in absorbance at 340 nm. The rate of decrease in A340 is directly proportional to GPX4 activity. The GPX4 inhibitor mL-162 is included as a positive control.
Needed but not supplied: Please download the kit booklet to verify if UltraPure Water (Milli-Q or equivalent) or any other components are needed for this assay.
WARNING This product is not for human or veterinary use.
Technical Information
| Synonyms |
|
| Origin | Animal/Bovine |
Shipping & Storage Information
| Storage | -80°C |
| Shipping | Dry ice in continental US; may vary elsewhere |
| Stability | ≥ 2 years |
| SKU | CAYM-701880-96WELL |
|---|---|
| Supplier Part Number | 701880-96WELL |
| UM | EA |
| UNSPSC | 41116012 |
| Manufacturer | Cayman |
| Temperature | -80 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | Y |
| Energy Star | No |
| Green | No |
| Controlled | N |