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Cayman cGAS Inhibitor Screening Assay Kit, 96 solid wells
List Price $679.00 Your Price $679.00
Cayman cGAS Inhibitor Screening Assay Kit, 96 solid wells-CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-701930-96SOLID
MFG.PART: 701930-96SOLID
UNSPSC: 60104007
Manufacturer: Cayman
Product Description
Cayman’s cGAS Inhibitor Screening Assay Kit provides a robust and easy-to-use platform for identifying novel inhibitors of human cGAS, which is a cytosolic dsDNA sensor that detects microbial pathogens. The assay directly measures 2’3’-cGAMP produced by cGAS in the presence of DNA, ATP, and GTP. The cyclic dinucleotide product of that reaction is quantified via ELISA using a 2’3’-cGAMP-specific antiserum. The cGAS inhibitor Cu-76 is included as a positive control.
The ELISA portion of Cayman’s cGAS Inhibitor Screening Assay Kit is a competitive assay with a range of 4.57-10,000 pM, a midpoint of approximately 300 pM (50% B/B0), and a sensitivity (80% B/B0) of approximately 50 pM.
Needed but not supplied: Please download the kit booklet to verify if UltraPure Water (Milli-Q or equivalent) or any other components are needed for this assay.
WARNING This product is not for human or veterinary use.
Technical Information
| Synonyms |
|
| Limit of Detection | 5.0 pM |
| Assay Range | 4.6-10,000 pM |
| Sensitivity | 48.4 pM |
| License | This product was developed in conjunction with BIOLOG Life Science Institute. |
| Origin | Animal/Bovine, Animal/Rabbit |
Shipping & Storage Information
| Storage | -80°C |
| Shipping | Dry ice in continental US; may vary elsewhere |
| Stability | ≥ 6 months |
| SKU | CAYM-701930-96SOLID |
|---|---|
| Supplier Part Number | 701930-96SOLID |
| UM | EA |
| UNSPSC | 60104007 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -80 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | Y |
| Energy Star | No |
| Green | No |
| Controlled | N |