Cayman SARS-CoV-2 Main Protease Inhibitor Screening Assay Kit, 96 wells

Product Description

Cayman’s SARS-CoV-2 Main Protease Inhibitor Screening Assay Kit provides a robust and easy-to-use platform for identifying novel inhibitors of SARS-CoV-2 M^pro, one of the proteases required for processing viral polyproteins into non-structural proteins. The assay uses a SARS-CoV-2 M^pro-specific fluorogenic substrate containing a cleavage site found between nsp4 and nsp5. SARS-CoV-2 M^pro cleaves this substrate separating an EDANS fluorophore from a Dabcyl quencher generating free EDANS, which can be easily quantified using a fluorescence plate reader at excitation and emission wavelengths of 340 and 490 nm, respectively. The SARS-CoV-2 M^pro inhibitor GC376 is included as a positive control.

Needed but not supplied: Please download the kit booklet to verify if UltraPure Water (Milli-Q or equivalent) or any other components are needed for this assay.

WARNING This product is not for human or veterinary use.

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