Cell Signaling Nck1 (5b7) Mouse mAb

Name: Cell Signaling Nck1 (5b7) Mouse mAb
SKU: CSSPQ-12778S
Price: 348.00 USD

List Price $348.00 Your Price $348.00

Cell Signaling Nck1 (5b7) Mouse mAb - CSSPQ (Additional S&H or Hazmat Fees May Apply)

NETA PART: CSSPQ-12778S

MFG.PART: 12778S

UNSPSC: 12352203

Manufacturer: Cell Signaling

Size	100 µl
Reactivity	H M R Hm Mk
Sensitivity	Endogenous
Molecular Weight (kDa)	47
Source/Isotype	Mouse IgG1
Application/Dilution	{Western Blotting: 1:1000}
Storage	Supplied in 10 mm sodium HEPES (pH 7.5), 150 mm NaCl, 100 µg/mL BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
Specificity/Sensitivity	NCK1 (5B7) Mouse mAb recognizes endogenous levels of total NCK1 protein.
Species Reactivity	Human, Mouse, Rat, Hamster, Monkey
Source/Purification	Monoclonal antibody is produced by immunizing animals with recombinant protein corresponding to a fragment of human NCK1 protein.
Background	NCK1 (also known as NCK or NCKα) is a broadly expressed oncogenic adapter protein consisting of three SH3 domains and one SH2 domain (1-3). NCK1 becomes phosphorylated upon activation of variety of cell surface receptors and is involved in actin cytoskeletal organization induced by many stimuli (4-6). NCK2 (also known as NCKβ), a homolog of NCK1, has an overlapping expression pattern and redundant functions with NCK1 (7).