Cell Signaling Syntaxin 6 (C34b2) Rabbit mAb

Name: Cell Signaling Syntaxin 6 (C34b2) Rabbit mAb
SKU: CSSPQ-2869T
Price: 148.00 USD

List Price $148.00 Your Price $148.00

Cell Signaling Syntaxin 6 (C34b2) Rabbit mAb - CSSPQ (Additional S&H or Hazmat Fees May Apply)

NETA PART: CSSPQ-2869T

MFG.PART: 2869T

UNSPSC: 12352203

Manufacturer: Cell Signaling

Size	20 µl
Reactivity	H M R
Sensitivity	Endogenous
Molecular Weight (kDa)	32
Source/Isotype	Rabbit IgG
Application/Dilution	{Western Blotting: 1:2000, Immunoprecipitation: 1:50, Immunofluorescence (Immunocytochemistry): 1:50 - 1:100}
Storage	Supplied in 10 mm sodium HEPES (pH 7.5), 150 mm NaCl, 100 µg/mL BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
Specificity/Sensitivity	Syntaxin 6 (C34B2) Rabbit mAb detects endogenous levels of total syntaxin 6 protein.
Species Reactivity	Human, Mouse, Rat
Source/Purification	Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Tyr140 of mouse syntaxin 6 protein.
Background	Syntaxin 6 is a ubiquitously expressed S25C family member of the SNARE proteins (1,2). The protein has an amino-terminal H1 domain followed by an H2 SNARE domain and a carboxy-terminal membrane anchor (3). Syntaxin 6 protein is localized to the trans-Golgi and within endosomes and regulates membrane trafficking by partnering with a variety of other SNARE proteins (3-5). Depending on cell type and SNARE parter, syntaxin 6 is involved in the regulation of GLUT4 trafficking, neutrophil exocytosis and granule secretion (6-10).