Cell Signaling Parkin (Prk8) Mouse mAb

Name: Cell Signaling Parkin (Prk8) Mouse mAb
SKU: CSSPQ-4211T
Price: 148.00 USD

List Price $148.00 Your Price $148.00

Cell Signaling Parkin (Prk8) Mouse mAb - CSSPQ (Additional S&H or Hazmat Fees May Apply)

NETA PART: CSSPQ-4211T

MFG.PART: 4211T

UNSPSC: 12352203

Manufacturer: Cell Signaling

Size	20 µl
Reactivity	H M R
Sensitivity	Endogenous
Molecular Weight (kDa)	50
Source/Isotype	Mouse IgG2b
Application/Dilution	{Western Blotting: 1:1000, Immunoprecipitation: 1:50}
Storage	Supplied in 10 mm sodium HEPES (pH 7.5), 150 mm NaCl, 100 µg/mL BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
Specificity/Sensitivity	Parkin (Prk8) Mouse mAb detects endogenous levels of total parkin protein.
Species Reactivity	Human, Mouse, Rat
Source/Purification	Monoclonal antibody is produced by immunizing animals with human recombinant parkin and the epitope maps to the carboxy terminus of the protein.
Background	Parkin is a protein of 465 amino acids with an amino-terminal ubiquitin domain and a carboxy-terminal RING-box (1). In the case of autosomal recessive juvenile Parkinsonism (AR-JP), deletions have been found in the gene on chromosome 6 encoding the protein Parkin (2).